Fabrication and Printing of Multi-material Hydrogels View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018

AUTHORS

Navein Arumugasaamy , Hannah B. Baker , David S. Kaplan , Peter C. W. Kim , John P. Fisher

ABSTRACT

Bioprinting has emerged over the past decade as a prominent technology in the field of tissue engineering. This enables fabrication of cell-laden hydrogels with precise control over the architecture of the scaffold and the location of cells, growth factors, and other biological cues of interest. We first discuss the challenges that exist in terms of choosing a bioprinter, ensuring mechanical support and printability of a material, and minimizing cellular stress for cell-laden prints. We then explain the different crosslinking methods commonly used in hydrogel printing and approaches to alter bioink crosslinking mechanisms. We discuss material selection for bioprinting with elaboration on common materials that have been used and a review of multi-material prints involving hydrogels. We also explore the use of a single, mixed bioink to fabricate complex but homogeneous constructs and multiple, independent bioinks to fabricate complex heterogeneous tissue constructs within the multi-material review. We conclude with a summary of the current state of the field and an outlook on future research. More... »

PAGES

397-430

Book

TITLE

3D Printing and Biofabrication

ISBN

978-3-319-45443-6
978-3-319-45444-3

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-45444-3_13

DOI

http://dx.doi.org/10.1007/978-3-319-45444-3_13

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1104265019


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