Pixium Vision: First Clinical Results and Innovative Developments View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016-11-25

AUTHORS

Ralf Hornig , Marcus Dapper , Eric Le Joliff , Robert Hill , Khalid Ishaque , Christoph Posch , Ryad Benosman , Yannick LeMer , José-Alain Sahel , Serge Picaud

ABSTRACT

Visual prostheses or Vision Restoration Systems (VRSs) aim to provide blind patients with useful visual information for face, shape, and object recognition, as well as reading and independent locomotion. VRS are specifically designed for patients having lost their photoreceptors. The loss of photoreceptors can either result from hereditary genetic retinal diseases such as retinitis pigmentosa or more complex diseases such as age-related macular degeneration. Visual restoration is achieved by electrically stimulating the residual retinal circuit. After successful clinical trials by others, Pixium Vision and its partners are developing two VRS solutions for blind patients: an epi-retinal and a sub-retinal approach. This chapter describes the specificities of the epi-retinal IRISTM VRS that has obtained the European CE cerfication mark, and also discuss the associated innovations developed at the Vision Institute for future VRS models. More... »

PAGES

99-113

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-41876-6_8

DOI

http://dx.doi.org/10.1007/978-3-319-41876-6_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1085995168


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1113", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Ophthalmology and Optometry", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Pixium Vision SA, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.509855.4", 
          "name": [
            "Pixium Vision SA, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hornig", 
        "givenName": "Ralf", 
        "id": "sg:person.01353367265.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353367265.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pixium Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.509855.4", 
          "name": [
            "Pixium Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dapper", 
        "givenName": "Marcus", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pixium Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.509855.4", 
          "name": [
            "Pixium Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le Joliff", 
        "givenName": "Eric", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pixium Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.509855.4", 
          "name": [
            "Pixium Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hill", 
        "givenName": "Robert", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pixium Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.509855.4", 
          "name": [
            "Pixium Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishaque", 
        "givenName": "Khalid", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Posch", 
        "givenName": "Christoph", 
        "id": "sg:person.013646451552.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013646451552.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Benosman", 
        "givenName": "Ryad", 
        "id": "sg:person.01003437362.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003437362.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fondation Ophtalmologique Adolphe de Rothschild, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.417888.a", 
          "name": [
            "Fondation Ophtalmologique Adolphe de Rothschild, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "LeMer", 
        "givenName": "Yannick", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academie des Sciences, Paris, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France", 
            "Fondation Ophtalmologique Adolphe de Rothschild, Paris, France", 
            "CHNO des Quinze-Vingts, Paris, France", 
            "Academie des Sciences, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sahel", 
        "givenName": "Jos\u00e9-Alain", 
        "id": "sg:person.01104041722.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104041722.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "INSERM, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Picaud", 
        "givenName": "Serge", 
        "id": "sg:person.0642273724.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642273724.04"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2016-11-25", 
    "datePublishedReg": "2016-11-25", 
    "description": "Visual prostheses or Vision Restoration Systems (VRSs) aim to provide blind patients with useful visual information for face, shape, and object recognition, as well as reading and independent locomotion. VRS are specifically designed for patients having lost their photoreceptors. The loss of photoreceptors can either result from hereditary genetic retinal diseases such as retinitis pigmentosa or more complex diseases such as age-related macular degeneration. Visual restoration is achieved by electrically stimulating the residual retinal circuit. After successful clinical trials by others, Pixium Vision and its partners are developing two VRS solutions for blind patients: an epi-retinal and a sub-retinal approach. This chapter describes the specificities of the epi-retinal IRISTM VRS that has obtained the European CE cerfication mark, and also discuss the associated innovations developed at the Vision Institute for future VRS models.", 
    "editor": [
      {
        "familyName": "Gabel", 
        "givenName": "Veit Peter", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-319-41876-6_8", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-319-41874-2", 
        "978-3-319-41876-6"
      ], 
      "name": "Artificial Vision", 
      "type": "Book"
    }, 
    "keywords": [
      "blind patients", 
      "age-related macular degeneration", 
      "loss of photoreceptors", 
      "successful clinical trials", 
      "first clinical results", 
      "genetic retinal disease", 
      "clinical results", 
      "clinical trials", 
      "macular degeneration", 
      "retinal circuits", 
      "visual restoration", 
      "Vision Institute", 
      "retinal diseases", 
      "retinitis pigmentosa", 
      "patients", 
      "visual prosthesis", 
      "disease", 
      "independent locomotion", 
      "complex diseases", 
      "photoreceptors", 
      "degeneration", 
      "pigmentosa", 
      "trials", 
      "prosthesis", 
      "visual information", 
      "useful visual information", 
      "specificity", 
      "restoration", 
      "Institute", 
      "locomotion", 
      "loss", 
      "partners", 
      "development", 
      "vision", 
      "results", 
      "recognition", 
      "face", 
      "information", 
      "model", 
      "approach", 
      "restoration system", 
      "chapter", 
      "system", 
      "marks", 
      "circuit", 
      "shape", 
      "innovation", 
      "solution", 
      "VRS model", 
      "innovative development"
    ], 
    "name": "Pixium Vision: First Clinical Results and Innovative Developments", 
    "pagination": "99-113", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1085995168"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-319-41876-6_8"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-319-41876-6_8", 
      "https://app.dimensions.ai/details/publication/pub.1085995168"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-05-20T07:45", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/chapter/chapter_316.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-3-319-41876-6_8"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-41876-6_8'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-41876-6_8'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-41876-6_8'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-41876-6_8'


 

This table displays all metadata directly associated to this object as RDF triples.

184 TRIPLES      23 PREDICATES      75 URIs      67 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-319-41876-6_8 schema:about anzsrc-for:11
2 anzsrc-for:1109
3 anzsrc-for:1113
4 schema:author N4df7692245854570b962d0a10f266fc0
5 schema:datePublished 2016-11-25
6 schema:datePublishedReg 2016-11-25
7 schema:description Visual prostheses or Vision Restoration Systems (VRSs) aim to provide blind patients with useful visual information for face, shape, and object recognition, as well as reading and independent locomotion. VRS are specifically designed for patients having lost their photoreceptors. The loss of photoreceptors can either result from hereditary genetic retinal diseases such as retinitis pigmentosa or more complex diseases such as age-related macular degeneration. Visual restoration is achieved by electrically stimulating the residual retinal circuit. After successful clinical trials by others, Pixium Vision and its partners are developing two VRS solutions for blind patients: an epi-retinal and a sub-retinal approach. This chapter describes the specificities of the epi-retinal IRISTM VRS that has obtained the European CE cerfication mark, and also discuss the associated innovations developed at the Vision Institute for future VRS models.
8 schema:editor N6488c93f17df449688ef3ae8731cd4c7
9 schema:genre chapter
10 schema:inLanguage en
11 schema:isAccessibleForFree false
12 schema:isPartOf N4795fdc4d2594f46a29bfa032d0f1236
13 schema:keywords Institute
14 VRS model
15 Vision Institute
16 age-related macular degeneration
17 approach
18 blind patients
19 chapter
20 circuit
21 clinical results
22 clinical trials
23 complex diseases
24 degeneration
25 development
26 disease
27 face
28 first clinical results
29 genetic retinal disease
30 independent locomotion
31 information
32 innovation
33 innovative development
34 locomotion
35 loss
36 loss of photoreceptors
37 macular degeneration
38 marks
39 model
40 partners
41 patients
42 photoreceptors
43 pigmentosa
44 prosthesis
45 recognition
46 restoration
47 restoration system
48 results
49 retinal circuits
50 retinal diseases
51 retinitis pigmentosa
52 shape
53 solution
54 specificity
55 successful clinical trials
56 system
57 trials
58 useful visual information
59 vision
60 visual information
61 visual prosthesis
62 visual restoration
63 schema:name Pixium Vision: First Clinical Results and Innovative Developments
64 schema:pagination 99-113
65 schema:productId N3bca9ac905f24f4896e470553c559bb5
66 N3d2b036962bc44c8bd9dfa811302ea23
67 schema:publisher N0eaa58b95f354e1aaa24e8b9575eb31c
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085995168
69 https://doi.org/10.1007/978-3-319-41876-6_8
70 schema:sdDatePublished 2022-05-20T07:45
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher Ncf62ce294bfe4689ad6ab606b687d7ea
73 schema:url https://doi.org/10.1007/978-3-319-41876-6_8
74 sgo:license sg:explorer/license/
75 sgo:sdDataset chapters
76 rdf:type schema:Chapter
77 N057cdc40ba194dc8a7cbfc3dcc0485a0 schema:affiliation grid-institutes:grid.509855.4
78 schema:familyName Hill
79 schema:givenName Robert
80 rdf:type schema:Person
81 N0eaa58b95f354e1aaa24e8b9575eb31c schema:name Springer Nature
82 rdf:type schema:Organisation
83 N11791b7c949e4af0bbc664535cc77b85 rdf:first Na0ae5407ec5449e6add715160056a9bd
84 rdf:rest N8b0bbe5740c04341a869386619118587
85 N29f7418fd39841e282f6fb7d417e5aae rdf:first sg:person.01003437362.65
86 rdf:rest N417a2a8415494bce89d3a8fc4061a856
87 N3bca9ac905f24f4896e470553c559bb5 schema:name dimensions_id
88 schema:value pub.1085995168
89 rdf:type schema:PropertyValue
90 N3d2b036962bc44c8bd9dfa811302ea23 schema:name doi
91 schema:value 10.1007/978-3-319-41876-6_8
92 rdf:type schema:PropertyValue
93 N417a2a8415494bce89d3a8fc4061a856 rdf:first Nfbf7013cc0f44a8eb171d3ed3a9c12f8
94 rdf:rest N5f4d80af24074fa9ac265e687721f0fa
95 N47879fee34e9456fb5182f8922c392f0 rdf:first Nd86dab8b4cdf49cbbe1610007b40a064
96 rdf:rest Nb1641703167143468fdd6327e1345caf
97 N4795fdc4d2594f46a29bfa032d0f1236 schema:isbn 978-3-319-41874-2
98 978-3-319-41876-6
99 schema:name Artificial Vision
100 rdf:type schema:Book
101 N4df7692245854570b962d0a10f266fc0 rdf:first sg:person.01353367265.11
102 rdf:rest N47879fee34e9456fb5182f8922c392f0
103 N5e9c455aeac7452eb09895addd15905a schema:familyName Gabel
104 schema:givenName Veit Peter
105 rdf:type schema:Person
106 N5f4d80af24074fa9ac265e687721f0fa rdf:first sg:person.01104041722.66
107 rdf:rest N62135e42946b4deaab73e697c536eea5
108 N62135e42946b4deaab73e697c536eea5 rdf:first sg:person.0642273724.04
109 rdf:rest rdf:nil
110 N6488c93f17df449688ef3ae8731cd4c7 rdf:first N5e9c455aeac7452eb09895addd15905a
111 rdf:rest rdf:nil
112 N8b0bbe5740c04341a869386619118587 rdf:first sg:person.013646451552.85
113 rdf:rest N29f7418fd39841e282f6fb7d417e5aae
114 N99e1365c43954a4aa0c17d1754add0ce rdf:first N057cdc40ba194dc8a7cbfc3dcc0485a0
115 rdf:rest N11791b7c949e4af0bbc664535cc77b85
116 Na0ae5407ec5449e6add715160056a9bd schema:affiliation grid-institutes:grid.509855.4
117 schema:familyName Ishaque
118 schema:givenName Khalid
119 rdf:type schema:Person
120 Nb1641703167143468fdd6327e1345caf rdf:first Nd314fab3479140bb8173e1bc2cc1101d
121 rdf:rest N99e1365c43954a4aa0c17d1754add0ce
122 Ncf62ce294bfe4689ad6ab606b687d7ea schema:name Springer Nature - SN SciGraph project
123 rdf:type schema:Organization
124 Nd314fab3479140bb8173e1bc2cc1101d schema:affiliation grid-institutes:grid.509855.4
125 schema:familyName Le Joliff
126 schema:givenName Eric
127 rdf:type schema:Person
128 Nd86dab8b4cdf49cbbe1610007b40a064 schema:affiliation grid-institutes:grid.509855.4
129 schema:familyName Dapper
130 schema:givenName Marcus
131 rdf:type schema:Person
132 Nfbf7013cc0f44a8eb171d3ed3a9c12f8 schema:affiliation grid-institutes:grid.417888.a
133 schema:familyName LeMer
134 schema:givenName Yannick
135 rdf:type schema:Person
136 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
137 schema:name Medical and Health Sciences
138 rdf:type schema:DefinedTerm
139 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
140 schema:name Neurosciences
141 rdf:type schema:DefinedTerm
142 anzsrc-for:1113 schema:inDefinedTermSet anzsrc-for:
143 schema:name Ophthalmology and Optometry
144 rdf:type schema:DefinedTerm
145 sg:person.01003437362.65 schema:affiliation grid-institutes:None
146 schema:familyName Benosman
147 schema:givenName Ryad
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01003437362.65
149 rdf:type schema:Person
150 sg:person.01104041722.66 schema:affiliation grid-institutes:None
151 schema:familyName Sahel
152 schema:givenName José-Alain
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01104041722.66
154 rdf:type schema:Person
155 sg:person.01353367265.11 schema:affiliation grid-institutes:grid.509855.4
156 schema:familyName Hornig
157 schema:givenName Ralf
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353367265.11
159 rdf:type schema:Person
160 sg:person.013646451552.85 schema:affiliation grid-institutes:None
161 schema:familyName Posch
162 schema:givenName Christoph
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013646451552.85
164 rdf:type schema:Person
165 sg:person.0642273724.04 schema:affiliation grid-institutes:None
166 schema:familyName Picaud
167 schema:givenName Serge
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642273724.04
169 rdf:type schema:Person
170 grid-institutes:None schema:alternateName Academie des Sciences, Paris, France
171 INSERM, Sorbonne Universités, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France
172 schema:name Academie des Sciences, Paris, France
173 CHNO des Quinze-Vingts, Paris, France
174 Fondation Ophtalmologique Adolphe de Rothschild, Paris, France
175 INSERM, Sorbonne Universités, UPMC Univ Paris 06, UMR_S968, CNRS UMR7210, Institut de la Vision, Paris, France
176 rdf:type schema:Organization
177 grid-institutes:grid.417888.a schema:alternateName Fondation Ophtalmologique Adolphe de Rothschild, Paris, France
178 schema:name Fondation Ophtalmologique Adolphe de Rothschild, Paris, France
179 rdf:type schema:Organization
180 grid-institutes:grid.509855.4 schema:alternateName Pixium Vision SA, Paris, France
181 Pixium Vision, Paris, France
182 schema:name Pixium Vision SA, Paris, France
183 Pixium Vision, Paris, France
184 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...