Phase-Contrast Clinical Breast CT: Optimization of Imaging Setups and Reconstruction Workflows View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016-06-17

AUTHORS

Giuliana Tromba , Serena Pacilè , Yakov I. Nesterets , Francesco Brun , Christian Dullin , Diego Dreossi , Sheridan C. Mayo , Andrew W. Stevenson , Konstantin M. Pavlov , Markus J. Kitchen , Darren Thompson , Jeremy M. C. Brown , Darren Lockie , Maura Tonutti , Fulvio Stacul , Fabrizio Zanconati , Agostino Accardo , T. E. Gureyev

ABSTRACT

We present the outcomes of combined feasibility studies carried out at Elettra and Australian Synchrotron to evaluate novel protocols for three-dimensional (3D) mammographic phase contrast imaging. A custom designed plastic phantom and some tissue samples have been studied at diverse resolution scales and experimental conditions. Several computed tomography (CT) reconstruction algorithms with different pre-processing and post-processing steps have been considered. Special attention was paid to the effect of phase retrieval on the diagnostic value of the reconstructed images. The images were quantitatively evaluated using objective quality indices in comparison with subjective assessments performed by three experienced radiologists and one pathologist. We show that the propagation-based phase-contrast imaging (PBI) leads to substantial improvement to the contrast-to-noise and to the intrinsic quality of the reconstructed CT images compared with conventional techniques as well as to an important reduction of the delivered doses, thus opening the way to clinical implementations. More... »

PAGES

625-634

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-41546-8_78

DOI

http://dx.doi.org/10.1007/978-3-319-41546-8_78

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020389233


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