Urothelial Carcinoma with Variant Histology: Sarcomatoid, Plasmacytoid, and Micropapillary View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Stephen B. Williams , Ashish M. Kamat

ABSTRACT

Approximately 80 % of bladder cancer is diagnosed as “conventional” urothelial carcinoma (UC) with 10–25 % nonurothelial and “variants” of urothelial carcinoma (UC). For the current discussion, variant histology will refer to any bladder malignancy other than pure UC. Furthermore, we have limited our review to the specific histologic variants sarcomatoid, plasmacytoid, and micropapillary bladder cancer. Before we discuss each of these variants in detail, we should mention that each of these histologic descriptions is based on morphologic features from H&E pathologic sections with little insight into their biology. Moreover, mixed histologies are often present (including so-called urothelial and nonurothelial carcinomas), for which the term variant histology is generally used. Figure 6.1 describes the histological classification of tumors arising from the urinary tract and was adapted from the 2004 World Health Organization classification of tumors. More... »

PAGES

95-108

Book

TITLE

Rare Genitourinary Tumors

ISBN

978-3-319-30044-3
978-3-319-30046-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-30046-7_6

DOI

http://dx.doi.org/10.1007/978-3-319-30046-7_6

DIMENSIONS

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55 schema:description Approximately 80 % of bladder cancer is diagnosed as “conventional” urothelial carcinoma (UC) with 10–25 % nonurothelial and “variants” of urothelial carcinoma (UC). For the current discussion, variant histology will refer to any bladder malignancy other than pure UC. Furthermore, we have limited our review to the specific histologic variants sarcomatoid, plasmacytoid, and micropapillary bladder cancer. Before we discuss each of these variants in detail, we should mention that each of these histologic descriptions is based on morphologic features from H&E pathologic sections with little insight into their biology. Moreover, mixed histologies are often present (including so-called urothelial and nonurothelial carcinomas), for which the term variant histology is generally used. Figure 6.1 describes the histological classification of tumors arising from the urinary tract and was adapted from the 2004 World Health Organization classification of tumors.
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