Diagnosis and Management of Hereditary Adrenal Cancer View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Anna Angelousi , Mihail Zilbermint , Annabel Berthon , Stéphanie Espiard , Constantine A. Stratakis

ABSTRACT

Benign adrenocortical tumours (ACT) are relatively frequent lesions; on the contrary, adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with unfavourable prognosis. Recent advances in the molecular understanding of adrenal cancer offer promise for better therapies in the future. Many of these advances stem from the molecular elucidation of genetic conditions predisposing to the development of ACC. Six main clinical syndromes have been described to be associated with hereditary adrenal cancer. In these conditions, genetic counselling plays an important role for the early detection and follow-up of the patients and the affected family members. More... »

PAGES

125-47

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-29998-3_8

DOI

http://dx.doi.org/10.1007/978-3-319-29998-3_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019813177

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27075352


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