Radioimmunoguided Surgery: Intraoperative Radioimmunodetection for the Radioguided Localization and Resection of Tumors View Full Text


Ontology type: schema:Chapter      Open Access: True


Chapter Info

DATE

2016

AUTHORS

Stephen P. Povoski , Cathy M. Mojzisik , Brandon J. Sullivan

ABSTRACT

Radioimmunoguided surgery is a specific application of radioguided surgery which involves intraoperative radioimmunodetection, using a handheld radiation detection device within the operating room in a real-time fashion, for the identification of a radiolabeled antibody or antibody fragment/derivative that has been administered to a patient prior to the time of attempted intraoperative detection and for the sole purpose of guiding the successful performance of the surgical procedure. This chapter discusses (1) the history and development of radioimmunoguided surgery, (2) tumor-associated antigens, (3) monoclonal antibodies, (4) clinical applications of radioimmunoguided surgery, and (5) the future clinical relevance of radioimmunoguided surgery in cancer diagnostics and cancer therapeutics (i.e., oncologic theranostics) as a potential powerful form of antigen-directed cancer surgery. More... »

PAGES

371-418

References to SciGraph publications

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  • Book

    TITLE

    Radioguided Surgery

    ISBN

    978-3-319-26049-5
    978-3-319-26051-8

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-319-26051-8_24

    DOI

    http://dx.doi.org/10.1007/978-3-319-26051-8_24

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017327957


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