Radioguided Surgery for Gastroenteropancreatic Neuroendocrine Tumors View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Nathan C. Hall , Christina Bluemel , Sergi Vidal-Sicart , Stephen P. Povoski

ABSTRACT

Gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) are rare neoplasms, but the incidence is rising. Surgery plays a central role in its management, as it is the only potentially curative treatment option for limited primary and recurrent disease and is critical in the surgical debulking and cytoreduction of advanced recurrent and metastatic disease. For preoperative detection of disease, gamma-emitting radiopharmaceuticals are available which can also be intraoperatively used for radioguided surgery. Most experience exists for 111In-octreotide, a radiopharmaceutical targeting agent specifically binding to somatostatin receptors expressed on the tumor cell surface. In comparison to traditional intraoperative inspection and palpation techniques, intraoperative localization using 111In-octreotide has demonstrated high sensitivity and detection rates. Recently, first promising results have been reported for utilization of intraoperative scintigraphic imaging in GEP-NETs in addition to more commonplace gamma probe localization. More... »

PAGES

299-311

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  • Book

    TITLE

    Radioguided Surgery

    ISBN

    978-3-319-26049-5
    978-3-319-26051-8

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-319-26051-8_19

    DOI

    http://dx.doi.org/10.1007/978-3-319-26051-8_19

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1034725100


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