Medical Evaluation of the Diabetic Patient for Pancreas Transplant View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Anup M Patel

ABSTRACT

Pancreas transplantation has the ability to restore normoglycemia in patients with insulin-dependent diabetes mellitus. As a result, it can potentially improve the quality of life and reduce the deleterious effects of the secondary complications of diabetes mellitus. Pancreas transplant surgery has a significant risk of surgical and infectious complications, although these risks are decreasing as more experience in the field is gained. A long-term mortality benefit for pancreas transplantation has not been shown and the selection of the potential pancreas transplant candidate must be strict. Risk factors for pancreas transplantation include older age, cardiovascular disease, and peripheral vascular disease. There are three different options for pancreas transplantation: (1) pancreas transplantation alone, (2) pancreas after kidney transplantation, and (3) simultaneous pancreas and kidney transplantation. Pancreas transplant alone is reserved for the patient who has adequate kidney function. The decision to perform pancreas after kidney transplantation or simultaneous pancreas and kidney transplantation should be made on an individual basis. Both options are superior to deceased donor kidney transplantation alone but do not appear to have a survival benefit compared to living donor kidney transplantation alone. More... »

PAGES

1-13

Book

TITLE

Contemporary Pancreas Transplantation

ISBN

978-3-319-20789-6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-20789-6_11-2

DOI

http://dx.doi.org/10.1007/978-3-319-20789-6_11-2

DIMENSIONS

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46 schema:description Pancreas transplantation has the ability to restore normoglycemia in patients with insulin-dependent diabetes mellitus. As a result, it can potentially improve the quality of life and reduce the deleterious effects of the secondary complications of diabetes mellitus. Pancreas transplant surgery has a significant risk of surgical and infectious complications, although these risks are decreasing as more experience in the field is gained. A long-term mortality benefit for pancreas transplantation has not been shown and the selection of the potential pancreas transplant candidate must be strict. Risk factors for pancreas transplantation include older age, cardiovascular disease, and peripheral vascular disease. There are three different options for pancreas transplantation: (1) pancreas transplantation alone, (2) pancreas after kidney transplantation, and (3) simultaneous pancreas and kidney transplantation. Pancreas transplant alone is reserved for the patient who has adequate kidney function. The decision to perform pancreas after kidney transplantation or simultaneous pancreas and kidney transplantation should be made on an individual basis. Both options are superior to deceased donor kidney transplantation alone but do not appear to have a survival benefit compared to living donor kidney transplantation alone.
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