JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1113", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Ophthalmology and Optometry", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "INSERM-DHOS CIC 503, Centre Hospitalier National d\u2019Ophtalmologie des Quinze-Vingts, 75012, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.415610.7", 
          "name": [
            "Inserm, U 968, UPMC University Paris 06, 75012, Paris, France", 
            "UMR_S 968, Institut de la Vision, UPMC University Paris 06, 75012, Paris, France", 
            "INSERM-DHOS CIC 503, Centre Hospitalier National d\u2019Ophtalmologie des Quinze-Vingts, 75012, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sennlaub", 
        "givenName": "Florian", 
        "id": "sg:person.01356263054.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356263054.39"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2015-12-02", 
    "datePublishedReg": "2015-12-02", 
    "description": "Age-related macular degeneration (AMD) is a complex multifactorial disease caused by the chronic interplay of genetic and environmental risk factors. One of the features observed in both early/intermediate and late forms of AMD is the subretinal accumulation of mononuclear phagocytes (MPs) such as inflammatory macrophages and microglial cells. The pathogenic importance of MP accumulation is not well understood and animal models might help defining it. In this chapter we first summarize the evidence and nature of subretinal inflammation in AMD. We review whether and how animal models of AMD risk factors influence subretinal inflammation. We outline \u201cprimary\u201d subretinal inflammation models, where the subretinal inflammation develops between originally healthy photoreceptors and retinal pigment epithelium (RPE) cells, due to a defect in tonic anti-inflammatory signals, deficient leukocyte elimination, or an autoimmune reaction. Finally, we give an overview of \u201csecondary inflammation\u201d models, where the subretinal MP accumulation has been shown to play a pathogenic role. The use of these AMD models might help to understand the origin and role of subretinal MP accumulation in AMD and identify drug targets to inhibit the possibly pathogenic accumulation of subretinal MPs or their neurotoxic and angiogenic mediators.", 
    "editor": [
      {
        "familyName": "Chan", 
        "givenName": "Chi-Chao", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-319-19434-9_4", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-319-19433-2", 
        "978-3-319-19434-9"
      ], 
      "name": "Animal Models of Ophthalmic Diseases", 
      "type": "Book"
    }, 
    "keywords": [
      "age-related macular degeneration", 
      "subretinal inflammation", 
      "animal models", 
      "mononuclear phagocytes", 
      "risk factors", 
      "macular degeneration", 
      "AMD risk factors", 
      "subretinal mononuclear phagocytes", 
      "retinal pigment epithelium cells", 
      "anti-inflammatory signals", 
      "environmental risk factors", 
      "pigment epithelium cells", 
      "complex multifactorial disease", 
      "subretinal accumulation", 
      "secondary inflammation", 
      "autoimmune reactions", 
      "microglial cells", 
      "inflammation model", 
      "pathogenic role", 
      "angiogenic mediators", 
      "pathogenic importance", 
      "pathogenic accumulation", 
      "healthy photoreceptors", 
      "inflammatory macrophages", 
      "inflammation", 
      "multifactorial disease", 
      "epithelium cells", 
      "MP accumulation", 
      "degeneration", 
      "AMD model", 
      "drug targets", 
      "cells", 
      "disease", 
      "macrophages", 
      "accumulation", 
      "phagocytes", 
      "age", 
      "factors", 
      "late form", 
      "mediators", 
      "role", 
      "photoreceptors", 
      "evidence", 
      "target", 
      "elimination", 
      "defects", 
      "use", 
      "model", 
      "importance", 
      "origin", 
      "features", 
      "overview", 
      "reaction", 
      "interplay", 
      "form", 
      "chapter", 
      "signals", 
      "nature"
    ], 
    "name": "Animal Models of Age-Related Macular Degeneration: Subretinal Inflammation", 
    "pagination": "51-65", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039491395"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-319-19434-9_4"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-319-19434-9_4", 
      "https://app.dimensions.ai/details/publication/pub.1039491395"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-05-20T07:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/chapter/chapter_432.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-3-319-19434-9_4"
  }
]

Download the RDF metadata as:  json-ld nt turtle xml License info

This table displays all metadata directly associated to this object as RDF triples.

120 TRIPLES      23 PREDICATES      82 URIs      75 LITERALS      7 BLANK NODES