Ocular Surface Reconstruction Using Cultivated Corneal and Oral Mucosal Epithelial Transplantation View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2017-11-17

AUTHORS

Tsutomu Inatomi , Takahiro Nakamura , Noriko Koizumi , Chie Sotozono , Shigeru Kinoshita

ABSTRACT

Cultivated epithelial sheet transplantation is a new surgical modality that involves tissue engineering and regenerative medicine to overcome the difficulties that are often observed in treating patients with severe ocular surface disease. These new therapeutic modalities have been shown to dramatically improve the clinical outcomes and prevent sight-threatening complications. Although strict follow-up and precise medical care are both essential for achieving a successful long-term outcome, understanding the specific characteristics of these surgical procedures and their associated complications is likewise crucial for avoiding complications that result in failure of the reconstructed ocular surface and, ultimately, loss of vision. This chapter specifically covers the indications and management strategies for using cultivated limbal epithelial transplantation (CLET) and cultivated oral mucosa epithelial transplantation (COMET) in patients with severe ocular surface disease. It highlights the challenges and the experiences we have gained at Kyoto Prefectural University over the last two decades. More... »

PAGES

349-361

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-15823-5_23

DOI

http://dx.doi.org/10.1007/978-3-319-15823-5_23

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1092726550


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