Near-Infrared Laser Photodynamic Therapy for Human Hepatocellular Carcinoma Cell Line Tumor with Indocyanine Green Fluorescence View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2015

AUTHORS

Junichi Kaneko , Yoshinori Inagaki , Takeaki Ishizawa , Norihiro Kokudo

ABSTRACT

It has recently been found that human hepatocellular carcinoma (HCC) preferentially takes up indocyanine green (ICG) in the clinical setting. We assessed the effectiveness of photodynamic therapy (PDT) using ICG and near-infrared (NIR) laser for HCC. HuH-7 (a well-differentiated human HCC) cell line was transplanted subcutaneously into mice. Mice were divided into groups: ICG administration only (ICG+ NIR−) and ICG and NIR laser exposure (ICG+ NIR+) at day 0. Mean tumor volume was significantly different between the ICG+ NIR+ group and the ICG+ NIR− group by day 9 (p < 0.01). PDT suppressed HuH-7 human HCC cell line tumor growth. More... »

PAGES

185-193

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-15678-1_19

DOI

http://dx.doi.org/10.1007/978-3-319-15678-1_19

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040990590


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