Preoperative Evaluation of Liver Function View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2017

AUTHORS

Kasia P. Cieslak , Roelof J. Bennink , Thomas M. van Gulik

ABSTRACT

In order to achieve microscopic radical resection margins and thus better survival, surgical treatment of hepatic tumors has become more aggressive in the last decade, resulting in an increased rate of complex and extended liver resections. Postoperative outcomes mainly depend on the size and quality of the future liver remnant (FLR). Liver resection, when performed in the absence of sufficient FLR, inevitably leads to post-resectional liver failure. The current gold standard in the preoperative assessment of FLR is computed tomography volumetry. Apart from the volume of liver remnant after resection, postoperative function of the liver remnant is directly related to the quality of liver parenchyma. The latter is mainly dictated by underlying diseases such as cirrhosis and steatosis, which are often inaccurately defined until microscopical examination after the resection. Post-resectional liver failure remains a point of major concern calling for accurate methods of preoperative FLR assessment. A wide spectrum of tests has become available in the past years, attesting to the fact that the ideal methodology has yet to be defined. The aim of this overview is to discuss the current modalities available and new perspectives in assessment of FLR in patients scheduled for major liver resection. More... »

PAGES

31-52

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  • Book

    TITLE

    Extreme Hepatic Surgery and Other Strategies

    ISBN

    978-3-319-13895-4
    978-3-319-13896-1

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-3-319-13896-1_3

    DOI

    http://dx.doi.org/10.1007/978-3-319-13896-1_3

    DIMENSIONS

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