Red Blood Cell Transfusion Trigger in Cardiac Disease View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2015

AUTHORS

Parasuram Krishnamoorthy , Debabrata Mukherjee , Saurav Chatterjee

ABSTRACT

There have been remarkable advancements in treating acute coronary syndrome with different angioplasty techniques, novel antithrombotic and antiplatelet agents, and heart failure therapies using mechanical assist devices. However, most of these interventions are done in patients with complex comorbidities, which lead to an increased risk of bleeding. Anemia is one of the most prevalent coexisting conditions in patients with heart failure and acute coronary syndrome. There is growing evidence that anemia in these patient populations is an independent predictor of mortality and adverse outcomes. Increasing the hemoglobin through blood transfusion should in theory increase oxygen delivery and reduce myocardial ischemia. However, there are several risks associated with transfusion. Randomized trials in some patient populations have demonstrated that restrictive use of blood transfusion, using a hemoglobin trigger of <7 g/dL, is associated with similar or even better outcomes compared with a liberal transfusion strategy using 10 g/dL as a transfusion trigger. However, it is not clear which strategy is safest for patients with ischemic heart disease or heart failure. The aim of this chapter is to describe and attempt to understand the pathophysiology of anemia in heart failure and ischemic heart disease and summarize recent advances and evidence behind using blood transfusion to treat anemia in patients with heart disease. More... »

PAGES

25-34

Book

TITLE

Transfusion in the Intensive Care Unit

ISBN

978-3-319-08734-4
978-3-319-08735-1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-08735-1_4

DOI

http://dx.doi.org/10.1007/978-3-319-08735-1_4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048211260


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HOW TO GET THIS DATA PROGRAMMATICALLY:

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curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-08735-1_4'

N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-08735-1_4'


 

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