Islet Cell Transplant View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2019-05-03

AUTHORS

Appakalai N. Balamurugan , Gopalakrishnan Loganathan , Benjamin Tweed , William W. Tucker , Venugopal Subhashree , Sri Prakash L. Mokshagundam , Michael G. Hughes , Stuart K. Williams

ABSTRACT

Exogenous insulin administration is currently the only treatment available for patients with type 1 diabetes, but it is not a cure. Long-term complications associated with the disease may be preventable with a treatment strategy that can provide better blood glucose control. The transplantation of isolated islets provides the potential to restore endogenous insulin production and reestablish normoglycemia. Significant progress has been made in the outcomes of clinical islet transplantation, reflecting improvements in nondiabetogenic immunosuppression and preparation of sufficient quantities of highly viable islets for transplantation. Islet transplantation represents a potential cure for patients with type 1 diabetes. More... »

PAGES

103-127

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-05257-1_2009

DOI

http://dx.doi.org/10.1007/978-3-319-05257-1_2009

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113950861


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.470916.d", 
          "name": [
            "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Balamurugan", 
        "givenName": "Appakalai N.", 
        "id": "sg:person.013566567154.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013566567154.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.470916.d", 
          "name": [
            "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Loganathan", 
        "givenName": "Gopalakrishnan", 
        "id": "sg:person.01372207601.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372207601.89"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.470916.d", 
          "name": [
            "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tweed", 
        "givenName": "Benjamin", 
        "id": "sg:person.013266436705.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013266436705.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.470916.d", 
          "name": [
            "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tucker", 
        "givenName": "William W.", 
        "id": "sg:person.016074221357.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016074221357.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "School of Biosciences and Technology, VIT University, Vellore, TN, India", 
          "id": "http://www.grid.ac/institutes/grid.412813.d", 
          "name": [
            "School of Biosciences and Technology, VIT University, Vellore, TN, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Subhashree", 
        "givenName": "Venugopal", 
        "id": "sg:person.01137412701.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137412701.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Endocrinology, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.266623.5", 
          "name": [
            "Department of Endocrinology, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mokshagundam", 
        "givenName": "Sri Prakash L.", 
        "id": "sg:person.01033600737.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033600737.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.470916.d", 
          "name": [
            "Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hughes", 
        "givenName": "Michael G.", 
        "id": "sg:person.016254340705.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016254340705.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bioficial Organs Program, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA", 
          "id": "http://www.grid.ac/institutes/grid.470916.d", 
          "name": [
            "Bioficial Organs Program, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Williams", 
        "givenName": "Stuart K.", 
        "id": "sg:person.01334153767.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334153767.05"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2019-05-03", 
    "datePublishedReg": "2019-05-03", 
    "description": "Exogenous insulin administration is currently the only treatment available for patients with type 1 diabetes, but it is not a cure. Long-term complications associated with the disease may be preventable with a treatment strategy that can provide better blood glucose control. The transplantation of isolated islets provides the potential to restore endogenous insulin production and reestablish normoglycemia. Significant progress has been made in the outcomes of clinical islet transplantation, reflecting improvements in nondiabetogenic immunosuppression and preparation of sufficient quantities of highly viable islets for transplantation. Islet transplantation represents a potential cure for patients with type 1 diabetes.", 
    "editor": [
      {
        "familyName": "Shah", 
        "givenName": "Ashesh Piyush", 
        "type": "Person"
      }, 
      {
        "familyName": "Doria", 
        "givenName": "Cataldo", 
        "type": "Person"
      }, 
      {
        "familyName": "Lim", 
        "givenName": "James W.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-319-05257-1_2009", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-319-05256-4", 
        "978-3-319-05257-1"
      ], 
      "name": "Contemporary Pancreas and Small Bowel Transplantation", 
      "type": "Book"
    }, 
    "keywords": [
      "type 1 diabetes", 
      "islet transplantation", 
      "good blood glucose control", 
      "long-term complications", 
      "endogenous insulin production", 
      "islet cell transplant", 
      "blood glucose control", 
      "clinical islet transplantation", 
      "exogenous insulin administration", 
      "cell transplant", 
      "glucose control", 
      "insulin administration", 
      "treatment strategies", 
      "potential cure", 
      "transplantation", 
      "insulin production", 
      "only treatment", 
      "viable islets", 
      "patients", 
      "diabetes", 
      "islets", 
      "cure", 
      "immunosuppression", 
      "complications", 
      "normoglycemia", 
      "transplant", 
      "disease", 
      "administration", 
      "outcomes", 
      "treatment", 
      "sufficient quantities", 
      "significant progress", 
      "control", 
      "improvement", 
      "strategies", 
      "potential", 
      "preparation", 
      "production", 
      "progress", 
      "quantity"
    ], 
    "name": "Islet Cell Transplant", 
    "pagination": "103-127", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113950861"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-319-05257-1_2009"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-319-05257-1_2009", 
      "https://app.dimensions.ai/details/publication/pub.1113950861"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-05-20T07:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/chapter/chapter_405.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-3-319-05257-1_2009"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-05257-1_2009'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-05257-1_2009'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-05257-1_2009'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-05257-1_2009'


 

This table displays all metadata directly associated to this object as RDF triples.

171 TRIPLES      23 PREDICATES      66 URIs      58 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-319-05257-1_2009 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 anzsrc-for:1107
4 schema:author Nc706d73b4ee7474b97486d57686c93ab
5 schema:datePublished 2019-05-03
6 schema:datePublishedReg 2019-05-03
7 schema:description Exogenous insulin administration is currently the only treatment available for patients with type 1 diabetes, but it is not a cure. Long-term complications associated with the disease may be preventable with a treatment strategy that can provide better blood glucose control. The transplantation of isolated islets provides the potential to restore endogenous insulin production and reestablish normoglycemia. Significant progress has been made in the outcomes of clinical islet transplantation, reflecting improvements in nondiabetogenic immunosuppression and preparation of sufficient quantities of highly viable islets for transplantation. Islet transplantation represents a potential cure for patients with type 1 diabetes.
8 schema:editor Nf6666e45ef51438a819ffd6401719cf7
9 schema:genre chapter
10 schema:inLanguage en
11 schema:isAccessibleForFree false
12 schema:isPartOf N164d7f68fbdd42cab1d94554fc13dfef
13 schema:keywords administration
14 blood glucose control
15 cell transplant
16 clinical islet transplantation
17 complications
18 control
19 cure
20 diabetes
21 disease
22 endogenous insulin production
23 exogenous insulin administration
24 glucose control
25 good blood glucose control
26 immunosuppression
27 improvement
28 insulin administration
29 insulin production
30 islet cell transplant
31 islet transplantation
32 islets
33 long-term complications
34 normoglycemia
35 only treatment
36 outcomes
37 patients
38 potential
39 potential cure
40 preparation
41 production
42 progress
43 quantity
44 significant progress
45 strategies
46 sufficient quantities
47 transplant
48 transplantation
49 treatment
50 treatment strategies
51 type 1 diabetes
52 viable islets
53 schema:name Islet Cell Transplant
54 schema:pagination 103-127
55 schema:productId N84cb1394ac9f43418ee1b72ef1f9cc2b
56 Ncf51a2c709d74b41839ac9dfef771395
57 schema:publisher N9fa3563afaf846bc9657e2b3d5f55607
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113950861
59 https://doi.org/10.1007/978-3-319-05257-1_2009
60 schema:sdDatePublished 2022-05-20T07:47
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher Na8e4cb3368fc4a49b4e268798a113dad
63 schema:url https://doi.org/10.1007/978-3-319-05257-1_2009
64 sgo:license sg:explorer/license/
65 sgo:sdDataset chapters
66 rdf:type schema:Chapter
67 N0112cd7e4c724fb39ae16a3421ae0499 schema:familyName Doria
68 schema:givenName Cataldo
69 rdf:type schema:Person
70 N08082facb8f44adfa2a773ce04cdbca1 schema:familyName Shah
71 schema:givenName Ashesh Piyush
72 rdf:type schema:Person
73 N15671074e7424f3c99e801131c52c431 rdf:first sg:person.01033600737.91
74 rdf:rest Nc88f2ca3d54844c6a032388f39c6212a
75 N164d7f68fbdd42cab1d94554fc13dfef schema:isbn 978-3-319-05256-4
76 978-3-319-05257-1
77 schema:name Contemporary Pancreas and Small Bowel Transplantation
78 rdf:type schema:Book
79 N3cc25a3b24204fabb6efa314f4fabc57 rdf:first sg:person.016074221357.45
80 rdf:rest Nb3195844d86949b48cfe95533161c686
81 N526fe7fb3d0f42acb169db9360346bf0 schema:familyName Lim
82 schema:givenName James W.
83 rdf:type schema:Person
84 N6fc16ddf26b84a3582763e1de330e917 rdf:first sg:person.01334153767.05
85 rdf:rest rdf:nil
86 N84cb1394ac9f43418ee1b72ef1f9cc2b schema:name doi
87 schema:value 10.1007/978-3-319-05257-1_2009
88 rdf:type schema:PropertyValue
89 N8e509ce6fb6b440db17d8b9a9382e557 rdf:first N526fe7fb3d0f42acb169db9360346bf0
90 rdf:rest rdf:nil
91 N977c30ef674f43dcb4ce5ee671b4205b rdf:first sg:person.01372207601.89
92 rdf:rest Nb65ec44bddd54027b73896ec0e039243
93 N9fa3563afaf846bc9657e2b3d5f55607 schema:name Springer Nature
94 rdf:type schema:Organisation
95 Na8e4cb3368fc4a49b4e268798a113dad schema:name Springer Nature - SN SciGraph project
96 rdf:type schema:Organization
97 Nb3195844d86949b48cfe95533161c686 rdf:first sg:person.01137412701.02
98 rdf:rest N15671074e7424f3c99e801131c52c431
99 Nb65ec44bddd54027b73896ec0e039243 rdf:first sg:person.013266436705.56
100 rdf:rest N3cc25a3b24204fabb6efa314f4fabc57
101 Nc706d73b4ee7474b97486d57686c93ab rdf:first sg:person.013566567154.60
102 rdf:rest N977c30ef674f43dcb4ce5ee671b4205b
103 Nc88f2ca3d54844c6a032388f39c6212a rdf:first sg:person.016254340705.59
104 rdf:rest N6fc16ddf26b84a3582763e1de330e917
105 Ncf51a2c709d74b41839ac9dfef771395 schema:name dimensions_id
106 schema:value pub.1113950861
107 rdf:type schema:PropertyValue
108 Nf26abe49df804d179f02db7e90ced016 rdf:first N0112cd7e4c724fb39ae16a3421ae0499
109 rdf:rest N8e509ce6fb6b440db17d8b9a9382e557
110 Nf6666e45ef51438a819ffd6401719cf7 rdf:first N08082facb8f44adfa2a773ce04cdbca1
111 rdf:rest Nf26abe49df804d179f02db7e90ced016
112 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
113 schema:name Medical and Health Sciences
114 rdf:type schema:DefinedTerm
115 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
116 schema:name Clinical Sciences
117 rdf:type schema:DefinedTerm
118 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
119 schema:name Immunology
120 rdf:type schema:DefinedTerm
121 sg:person.01033600737.91 schema:affiliation grid-institutes:grid.266623.5
122 schema:familyName Mokshagundam
123 schema:givenName Sri Prakash L.
124 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033600737.91
125 rdf:type schema:Person
126 sg:person.01137412701.02 schema:affiliation grid-institutes:grid.412813.d
127 schema:familyName Subhashree
128 schema:givenName Venugopal
129 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137412701.02
130 rdf:type schema:Person
131 sg:person.013266436705.56 schema:affiliation grid-institutes:grid.470916.d
132 schema:familyName Tweed
133 schema:givenName Benjamin
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013266436705.56
135 rdf:type schema:Person
136 sg:person.01334153767.05 schema:affiliation grid-institutes:grid.470916.d
137 schema:familyName Williams
138 schema:givenName Stuart K.
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334153767.05
140 rdf:type schema:Person
141 sg:person.013566567154.60 schema:affiliation grid-institutes:grid.470916.d
142 schema:familyName Balamurugan
143 schema:givenName Appakalai N.
144 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013566567154.60
145 rdf:type schema:Person
146 sg:person.01372207601.89 schema:affiliation grid-institutes:grid.470916.d
147 schema:familyName Loganathan
148 schema:givenName Gopalakrishnan
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372207601.89
150 rdf:type schema:Person
151 sg:person.016074221357.45 schema:affiliation grid-institutes:grid.470916.d
152 schema:familyName Tucker
153 schema:givenName William W.
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016074221357.45
155 rdf:type schema:Person
156 sg:person.016254340705.59 schema:affiliation grid-institutes:grid.470916.d
157 schema:familyName Hughes
158 schema:givenName Michael G.
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016254340705.59
160 rdf:type schema:Person
161 grid-institutes:grid.266623.5 schema:alternateName Department of Endocrinology, University of Louisville, Louisville, KY, USA
162 schema:name Department of Endocrinology, University of Louisville, Louisville, KY, USA
163 rdf:type schema:Organization
164 grid-institutes:grid.412813.d schema:alternateName School of Biosciences and Technology, VIT University, Vellore, TN, India
165 schema:name School of Biosciences and Technology, VIT University, Vellore, TN, India
166 rdf:type schema:Organization
167 grid-institutes:grid.470916.d schema:alternateName Bioficial Organs Program, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA
168 Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA
169 schema:name Bioficial Organs Program, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA
170 Clinical Islet Cell Laboratory, Department of Surgery, Cardiovascular Innovation Institute, University of Louisville, Louisville, KY, USA
171 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...