Bioactive Phytochemicals from Canadian Boreal Forest Species Used Traditionally by Eastern James Bay Cree Aboriginals to Treat Diabetes Mellitus View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

José A. Guerrero-Analco , Asim Muhammad , Ammar Saleem , Louis C. Martineau , Lina Musallam , Hoda M. Eid , Nan Shang , Paleah Black , Alain Currier , Pierre S. Haddad , John T. Arnason

ABSTRACT

Type-2 diabetes mellitus is a chronic metabolic disorder characterized by impaired insulin secretion and sensitivity, and is more pronounced among some indigenous populations due to their transition from traditional to modern diets, as well as their cultural disconnection from modern pharmacological treatment regimes. This is the case for the Cree Nations of Eeyou Istchee (CEI) of northern Quebec, where the age-adjusted prevalence of disease reached 29 %. The Canadian Institutes of Health Research Team in Aboriginal Antidiabetic Medicines is a multidisciplinary team aimed at alleviating the impact of this disease in the CEI by using a culturally adapted approach. A quantitative ethnobotanical study of traditional medicines conducted by our team in collaboration with Healers and Elders resulted in the identification of several potential antidiabetic plants. The crude extracts of these plants were tested in a comprehensive platform of in vitro bioassays designed to detect potential antidiabetic biological activities including: stimulation of glucose uptake in C2C12 muscle cells and potentiation of differentiation of 3T3-L1 pre-adipocytes indicating enhanced insulin sensitivity. These procedures allowed us to identify the most significant species from the biological activity viewpoint, and they were considered for further phytochemical characterization. The present report provides a comprehensive summary of the major biological activities and phytochemistry of these key Canadian boreal forest plants that demonstrated significant ethnobotanical evidence of antidiabetic activity and associated symptoms. More... »

PAGES

57-84

Book

TITLE

Phytochemicals – Biosynthesis, Function and Application

ISBN

978-3-319-04044-8
978-3-319-04045-5

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-319-04045-5_4

DOI

http://dx.doi.org/10.1007/978-3-319-04045-5_4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024630522


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "Centre for Advanced Research in Environmental Genomics, University of Ottawa, K1N6N5\u00a0Ottawa, ON, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guerrero-Analco", 
        "givenName": "Jos\u00e9 A.", 
        "id": "sg:person.01145121631.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145121631.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "Centre for Advanced Research in Environmental Genomics, University of Ottawa, K1N6N5\u00a0Ottawa, ON, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Muhammad", 
        "givenName": "Asim", 
        "id": "sg:person.0720305731.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720305731.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "Centre for Advanced Research in Environmental Genomics, University of Ottawa, K1N6N5\u00a0Ottawa, ON, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saleem", 
        "givenName": "Ammar", 
        "id": "sg:person.0604057331.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604057331.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Montreal", 
          "id": "https://www.grid.ac/institutes/grid.14848.31", 
          "name": [
            "Department of Pharmacology, Universit\u00e9 de Montr\u00e9al, H3T 1J4\u00a0Montr\u00e9al, QC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martineau", 
        "givenName": "Louis C.", 
        "id": "sg:person.01077011655.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077011655.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Montreal", 
          "id": "https://www.grid.ac/institutes/grid.14848.31", 
          "name": [
            "Department of Pharmacology, Universit\u00e9 de Montr\u00e9al, H3T 1J4\u00a0Montr\u00e9al, QC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Musallam", 
        "givenName": "Lina", 
        "id": "sg:person.0764151611.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764151611.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Montreal", 
          "id": "https://www.grid.ac/institutes/grid.14848.31", 
          "name": [
            "Department of Pharmacology, Universit\u00e9 de Montr\u00e9al, H3T 1J4\u00a0Montr\u00e9al, QC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Eid", 
        "givenName": "Hoda M.", 
        "id": "sg:person.01027011545.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027011545.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Montreal", 
          "id": "https://www.grid.ac/institutes/grid.14848.31", 
          "name": [
            "Department of Pharmacology, Universit\u00e9 de Montr\u00e9al, H3T 1J4\u00a0Montr\u00e9al, QC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shang", 
        "givenName": "Nan", 
        "id": "sg:person.01030673231.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030673231.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "Centre for Advanced Research in Environmental Genomics, University of Ottawa, K1N6N5\u00a0Ottawa, ON, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Black", 
        "givenName": "Paleah", 
        "id": "sg:person.0766223704.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766223704.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Canadian Institutes of Health Research Team in Aboriginal Antidiabetic Medicines, H3T 1J4\u00a0Montr\u00e9al, QC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Currier", 
        "givenName": "Alain", 
        "id": "sg:person.011211672451.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011211672451.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Montreal", 
          "id": "https://www.grid.ac/institutes/grid.14848.31", 
          "name": [
            "Department of Pharmacology, Universit\u00e9 de Montr\u00e9al, H3T 1J4\u00a0Montr\u00e9al, QC, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Haddad", 
        "givenName": "Pierre S.", 
        "id": "sg:person.01100400211.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100400211.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Ottawa", 
          "id": "https://www.grid.ac/institutes/grid.28046.38", 
          "name": [
            "Centre for Advanced Research in Environmental Genomics, University of Ottawa, K1N6N5\u00a0Ottawa, ON, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arnason", 
        "givenName": "John T.", 
        "id": "sg:person.01033034227.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033034227.11"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1750-3841.2009.01401.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002126361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1750-3841.2009.01401.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002126361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pca.1203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003636152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pca.1203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003636152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/y09-029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004948672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmcl.2004.04.062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007512760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jep.2012.04.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009065770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lfs.2007.12.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010183136"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/y07-108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010226762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/b2012-026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011464874"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/14786410802228827", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012310689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pca.970", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015932067"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mnfr.200900218", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019689846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mnfr.200900218", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019689846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2012/296432", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020838758"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diabres.2009.10.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021030777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1750-3841.2012.02934.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024898999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jep.2005.09.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027498321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jep.2005.09.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027498321"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1108/17506201211258414", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028491146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diabres.2009.10.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028972981"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/b07-052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029152639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/y06-018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030858859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2012/893426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032944717"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/b101676", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033419534", 
          "https://doi.org/10.1007/b101676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/b101676", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033419534", 
          "https://doi.org/10.1007/b101676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0031-9422(00)81813-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034044342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ecam/nep158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035001209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/h07-026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035807614"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1248/cpb.53.1519", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037253542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1248/cpb.53.1519", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037253542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mco.0b013e32831394b8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040421217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mco.0b013e32831394b8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040421217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12013-007-0008-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040833037", 
          "https://doi.org/10.1007/s12013-007-0008-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1517/14728222.12.1.91", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041088701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1248/cpb.54.1429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043438017"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci13505", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043705336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci13505", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043705336"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2006.109512", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045027093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jep.2009.10.026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045793699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jphysiol.2006.108506", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047646587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/db06-0900", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051275412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diacare.27.5.1047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051349743"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/b81-287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052767194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np1003005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056231235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np1003005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056231235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np3001317", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056231926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np980083l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056239195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np980083l", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056239195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np9801460", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056239243"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/np9801460", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056239243"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0028-1088394", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057108058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0029-1240991", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057207233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0030-1270968", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057234342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0031-1282395", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057243356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/mi.2.1.22", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062438256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1062438256", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/mi.2.1.22", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062438256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2741/2907", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070915051"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2741/3460", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070915655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/jappl.2001.91.3.1017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074866486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.bmb.a072627", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082708124"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014", 
    "datePublishedReg": "2014-01-01", 
    "description": "Type-2 diabetes mellitus is a chronic metabolic disorder characterized by impaired insulin secretion and sensitivity, and is more pronounced among some indigenous populations due to their transition from traditional to modern diets, as well as their cultural disconnection from modern pharmacological treatment regimes. This is the case for the Cree Nations of Eeyou Istchee (CEI) of northern Quebec, where the age-adjusted prevalence of disease reached 29\u2009%. The Canadian Institutes of Health Research Team in Aboriginal Antidiabetic Medicines is a multidisciplinary team aimed at alleviating the impact of this disease in the CEI by using a culturally adapted approach. A quantitative ethnobotanical study of traditional medicines conducted by our team in collaboration with Healers and Elders resulted in the identification of several potential antidiabetic plants. The crude extracts of these plants were tested in a comprehensive platform of in vitro bioassays designed to detect potential antidiabetic biological activities including: stimulation of glucose uptake in C2C12 muscle cells and potentiation of differentiation of 3T3-L1 pre-adipocytes indicating enhanced insulin sensitivity. These procedures allowed us to identify the most significant species from the biological activity viewpoint, and they were considered for further phytochemical characterization. The present report provides a comprehensive summary of the major biological activities and phytochemistry of these key Canadian boreal forest plants that demonstrated significant ethnobotanical evidence of antidiabetic activity and associated symptoms.", 
    "editor": [
      {
        "familyName": "Jetter", 
        "givenName": "Reinhard", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-3-319-04045-5_4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-319-04044-8", 
        "978-3-319-04045-5"
      ], 
      "name": "Phytochemicals \u2013 Biosynthesis, Function and Application", 
      "type": "Book"
    }, 
    "name": "Bioactive Phytochemicals from Canadian Boreal Forest Species Used Traditionally by Eastern James Bay Cree Aboriginals to Treat Diabetes Mellitus", 
    "pagination": "57-84", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-3-319-04045-5_4"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "75574f64654bdf028a61fd4fa369c05aa37d1e45e77c8745133d25e9968062c2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1024630522"
        ]
      }
    ], 
    "publisher": {
      "location": "Cham", 
      "name": "Springer International Publishing", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-3-319-04045-5_4", 
      "https://app.dimensions.ai/details/publication/pub.1024630522"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T10:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000258.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-3-319-04045-5_4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-04045-5_4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-04045-5_4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-04045-5_4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-3-319-04045-5_4'


 

This table displays all metadata directly associated to this object as RDF triples.

291 TRIPLES      23 PREDICATES      77 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-3-319-04045-5_4 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Neb5bcaae8abc4e2bb91410f0a6d0e7e6
4 schema:citation sg:pub.10.1007/b101676
5 sg:pub.10.1007/s12013-007-0008-7
6 https://app.dimensions.ai/details/publication/pub.1062438256
7 https://doi.org/10.1002/mnfr.200900218
8 https://doi.org/10.1002/pca.1203
9 https://doi.org/10.1002/pca.970
10 https://doi.org/10.1016/j.bmcl.2004.04.062
11 https://doi.org/10.1016/j.diabres.2009.10.006
12 https://doi.org/10.1016/j.diabres.2009.10.007
13 https://doi.org/10.1016/j.jep.2005.09.038
14 https://doi.org/10.1016/j.jep.2009.10.026
15 https://doi.org/10.1016/j.jep.2012.04.002
16 https://doi.org/10.1016/j.lfs.2007.12.021
17 https://doi.org/10.1016/s0031-9422(00)81813-0
18 https://doi.org/10.1021/np1003005
19 https://doi.org/10.1021/np3001317
20 https://doi.org/10.1021/np980083l
21 https://doi.org/10.1021/np9801460
22 https://doi.org/10.1055/s-0028-1088394
23 https://doi.org/10.1055/s-0029-1240991
24 https://doi.org/10.1055/s-0030-1270968
25 https://doi.org/10.1055/s-0031-1282395
26 https://doi.org/10.1080/14786410802228827
27 https://doi.org/10.1093/ecam/nep158
28 https://doi.org/10.1093/oxfordjournals.bmb.a072627
29 https://doi.org/10.1097/mco.0b013e32831394b8
30 https://doi.org/10.1108/17506201211258414
31 https://doi.org/10.1111/j.1750-3841.2009.01401.x
32 https://doi.org/10.1111/j.1750-3841.2012.02934.x
33 https://doi.org/10.1113/jphysiol.2006.108506
34 https://doi.org/10.1113/jphysiol.2006.109512
35 https://doi.org/10.1124/mi.2.1.22
36 https://doi.org/10.1139/b07-052
37 https://doi.org/10.1139/b2012-026
38 https://doi.org/10.1139/b81-287
39 https://doi.org/10.1139/h07-026
40 https://doi.org/10.1139/y06-018
41 https://doi.org/10.1139/y07-108
42 https://doi.org/10.1139/y09-029
43 https://doi.org/10.1152/jappl.2001.91.3.1017
44 https://doi.org/10.1155/2012/296432
45 https://doi.org/10.1155/2012/893426
46 https://doi.org/10.1172/jci13505
47 https://doi.org/10.1248/cpb.53.1519
48 https://doi.org/10.1248/cpb.54.1429
49 https://doi.org/10.1517/14728222.12.1.91
50 https://doi.org/10.2337/db06-0900
51 https://doi.org/10.2337/diacare.27.5.1047
52 https://doi.org/10.2741/2907
53 https://doi.org/10.2741/3460
54 schema:datePublished 2014
55 schema:datePublishedReg 2014-01-01
56 schema:description Type-2 diabetes mellitus is a chronic metabolic disorder characterized by impaired insulin secretion and sensitivity, and is more pronounced among some indigenous populations due to their transition from traditional to modern diets, as well as their cultural disconnection from modern pharmacological treatment regimes. This is the case for the Cree Nations of Eeyou Istchee (CEI) of northern Quebec, where the age-adjusted prevalence of disease reached 29 %. The Canadian Institutes of Health Research Team in Aboriginal Antidiabetic Medicines is a multidisciplinary team aimed at alleviating the impact of this disease in the CEI by using a culturally adapted approach. A quantitative ethnobotanical study of traditional medicines conducted by our team in collaboration with Healers and Elders resulted in the identification of several potential antidiabetic plants. The crude extracts of these plants were tested in a comprehensive platform of in vitro bioassays designed to detect potential antidiabetic biological activities including: stimulation of glucose uptake in C2C12 muscle cells and potentiation of differentiation of 3T3-L1 pre-adipocytes indicating enhanced insulin sensitivity. These procedures allowed us to identify the most significant species from the biological activity viewpoint, and they were considered for further phytochemical characterization. The present report provides a comprehensive summary of the major biological activities and phytochemistry of these key Canadian boreal forest plants that demonstrated significant ethnobotanical evidence of antidiabetic activity and associated symptoms.
57 schema:editor N9f894a21508f4d8a813c86dc7969099a
58 schema:genre chapter
59 schema:inLanguage en
60 schema:isAccessibleForFree false
61 schema:isPartOf N731b7b321e22483a99cb8ca85cec1cf6
62 schema:name Bioactive Phytochemicals from Canadian Boreal Forest Species Used Traditionally by Eastern James Bay Cree Aboriginals to Treat Diabetes Mellitus
63 schema:pagination 57-84
64 schema:productId N59a9bd6d13364a90b394f97c8f034b59
65 Nbc77a4ae15644a6ba47511d55680a4d5
66 Nde4bf39e376744e7bd291b37afe39995
67 schema:publisher Nabf5202c9aa64d5e90b72c192807e385
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024630522
69 https://doi.org/10.1007/978-3-319-04045-5_4
70 schema:sdDatePublished 2019-04-15T10:34
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher Nc9b5550aef8b4586b1617bd05a1179e8
73 schema:url http://link.springer.com/10.1007/978-3-319-04045-5_4
74 sgo:license sg:explorer/license/
75 sgo:sdDataset chapters
76 rdf:type schema:Chapter
77 N1fb74508e3e3468db5c76124c7665856 rdf:first sg:person.01030673231.28
78 rdf:rest N592c7cf0de7245d799b92b4bb9fb9997
79 N2359137b0bc747aeb4fe2138d9f45918 rdf:first sg:person.0720305731.19
80 rdf:rest N43a76cd3091949a098c1bf7fd1551d34
81 N3f04c305e919412a8c8da595550401ce rdf:first sg:person.01077011655.46
82 rdf:rest N77ea6f3ef4464dc2ac2ef5d870928259
83 N43a76cd3091949a098c1bf7fd1551d34 rdf:first sg:person.0604057331.85
84 rdf:rest N3f04c305e919412a8c8da595550401ce
85 N4ba151646d304607a97dcd80f11fa764 rdf:first sg:person.01033034227.11
86 rdf:rest rdf:nil
87 N4e87e821f8e14138ab260c336d368801 rdf:first sg:person.01100400211.44
88 rdf:rest N4ba151646d304607a97dcd80f11fa764
89 N592c7cf0de7245d799b92b4bb9fb9997 rdf:first sg:person.0766223704.64
90 rdf:rest N7dec0e68fe6e4446b28548a8bad524bf
91 N59a9bd6d13364a90b394f97c8f034b59 schema:name readcube_id
92 schema:value 75574f64654bdf028a61fd4fa369c05aa37d1e45e77c8745133d25e9968062c2
93 rdf:type schema:PropertyValue
94 N731b7b321e22483a99cb8ca85cec1cf6 schema:isbn 978-3-319-04044-8
95 978-3-319-04045-5
96 schema:name Phytochemicals – Biosynthesis, Function and Application
97 rdf:type schema:Book
98 N77ea6f3ef4464dc2ac2ef5d870928259 rdf:first sg:person.0764151611.27
99 rdf:rest N784c59a769d1477cb7bf6d4ed0b6bb22
100 N784c59a769d1477cb7bf6d4ed0b6bb22 rdf:first sg:person.01027011545.45
101 rdf:rest N1fb74508e3e3468db5c76124c7665856
102 N7dec0e68fe6e4446b28548a8bad524bf rdf:first sg:person.011211672451.17
103 rdf:rest N4e87e821f8e14138ab260c336d368801
104 N9f894a21508f4d8a813c86dc7969099a rdf:first Nfc007e71f0a34eedade9279b149d4ba5
105 rdf:rest rdf:nil
106 Nabf5202c9aa64d5e90b72c192807e385 schema:location Cham
107 schema:name Springer International Publishing
108 rdf:type schema:Organisation
109 Nbc77a4ae15644a6ba47511d55680a4d5 schema:name doi
110 schema:value 10.1007/978-3-319-04045-5_4
111 rdf:type schema:PropertyValue
112 Nc9b5550aef8b4586b1617bd05a1179e8 schema:name Springer Nature - SN SciGraph project
113 rdf:type schema:Organization
114 Nde4bf39e376744e7bd291b37afe39995 schema:name dimensions_id
115 schema:value pub.1024630522
116 rdf:type schema:PropertyValue
117 Ne94fe08f4e834a7ab685ba3cb4dd95fa schema:name Canadian Institutes of Health Research Team in Aboriginal Antidiabetic Medicines, H3T 1J4 Montréal, QC, Canada
118 rdf:type schema:Organization
119 Neb5bcaae8abc4e2bb91410f0a6d0e7e6 rdf:first sg:person.01145121631.27
120 rdf:rest N2359137b0bc747aeb4fe2138d9f45918
121 Nfc007e71f0a34eedade9279b149d4ba5 schema:familyName Jetter
122 schema:givenName Reinhard
123 rdf:type schema:Person
124 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
125 schema:name Medical and Health Sciences
126 rdf:type schema:DefinedTerm
127 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
128 schema:name Clinical Sciences
129 rdf:type schema:DefinedTerm
130 sg:person.01027011545.45 schema:affiliation https://www.grid.ac/institutes/grid.14848.31
131 schema:familyName Eid
132 schema:givenName Hoda M.
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027011545.45
134 rdf:type schema:Person
135 sg:person.01030673231.28 schema:affiliation https://www.grid.ac/institutes/grid.14848.31
136 schema:familyName Shang
137 schema:givenName Nan
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01030673231.28
139 rdf:type schema:Person
140 sg:person.01033034227.11 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
141 schema:familyName Arnason
142 schema:givenName John T.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033034227.11
144 rdf:type schema:Person
145 sg:person.01077011655.46 schema:affiliation https://www.grid.ac/institutes/grid.14848.31
146 schema:familyName Martineau
147 schema:givenName Louis C.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077011655.46
149 rdf:type schema:Person
150 sg:person.01100400211.44 schema:affiliation https://www.grid.ac/institutes/grid.14848.31
151 schema:familyName Haddad
152 schema:givenName Pierre S.
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100400211.44
154 rdf:type schema:Person
155 sg:person.011211672451.17 schema:affiliation Ne94fe08f4e834a7ab685ba3cb4dd95fa
156 schema:familyName Currier
157 schema:givenName Alain
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011211672451.17
159 rdf:type schema:Person
160 sg:person.01145121631.27 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
161 schema:familyName Guerrero-Analco
162 schema:givenName José A.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145121631.27
164 rdf:type schema:Person
165 sg:person.0604057331.85 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
166 schema:familyName Saleem
167 schema:givenName Ammar
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604057331.85
169 rdf:type schema:Person
170 sg:person.0720305731.19 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
171 schema:familyName Muhammad
172 schema:givenName Asim
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720305731.19
174 rdf:type schema:Person
175 sg:person.0764151611.27 schema:affiliation https://www.grid.ac/institutes/grid.14848.31
176 schema:familyName Musallam
177 schema:givenName Lina
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0764151611.27
179 rdf:type schema:Person
180 sg:person.0766223704.64 schema:affiliation https://www.grid.ac/institutes/grid.28046.38
181 schema:familyName Black
182 schema:givenName Paleah
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766223704.64
184 rdf:type schema:Person
185 sg:pub.10.1007/b101676 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033419534
186 https://doi.org/10.1007/b101676
187 rdf:type schema:CreativeWork
188 sg:pub.10.1007/s12013-007-0008-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040833037
189 https://doi.org/10.1007/s12013-007-0008-7
190 rdf:type schema:CreativeWork
191 https://app.dimensions.ai/details/publication/pub.1062438256 schema:CreativeWork
192 https://doi.org/10.1002/mnfr.200900218 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019689846
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1002/pca.1203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003636152
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1002/pca.970 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015932067
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/j.bmcl.2004.04.062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007512760
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/j.diabres.2009.10.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021030777
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/j.diabres.2009.10.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028972981
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/j.jep.2005.09.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027498321
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/j.jep.2009.10.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045793699
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/j.jep.2012.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009065770
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/j.lfs.2007.12.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010183136
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/s0031-9422(00)81813-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034044342
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1021/np1003005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056231235
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1021/np3001317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056231926
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1021/np980083l schema:sameAs https://app.dimensions.ai/details/publication/pub.1056239195
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1021/np9801460 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056239243
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1055/s-0028-1088394 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057108058
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1055/s-0029-1240991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057207233
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1055/s-0030-1270968 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057234342
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1055/s-0031-1282395 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057243356
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1080/14786410802228827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012310689
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1093/ecam/nep158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035001209
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1093/oxfordjournals.bmb.a072627 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082708124
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1097/mco.0b013e32831394b8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040421217
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1108/17506201211258414 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028491146
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1111/j.1750-3841.2009.01401.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002126361
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1111/j.1750-3841.2012.02934.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024898999
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1113/jphysiol.2006.108506 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047646587
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1113/jphysiol.2006.109512 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045027093
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1124/mi.2.1.22 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062438256
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1139/b07-052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029152639
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1139/b2012-026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011464874
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1139/b81-287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052767194
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1139/h07-026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035807614
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1139/y06-018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030858859
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1139/y07-108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010226762
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1139/y09-029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004948672
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1152/jappl.2001.91.3.1017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074866486
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1155/2012/296432 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020838758
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1155/2012/893426 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032944717
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1172/jci13505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043705336
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1248/cpb.53.1519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037253542
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1248/cpb.54.1429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043438017
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1517/14728222.12.1.91 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041088701
277 rdf:type schema:CreativeWork
278 https://doi.org/10.2337/db06-0900 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051275412
279 rdf:type schema:CreativeWork
280 https://doi.org/10.2337/diacare.27.5.1047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051349743
281 rdf:type schema:CreativeWork
282 https://doi.org/10.2741/2907 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070915051
283 rdf:type schema:CreativeWork
284 https://doi.org/10.2741/3460 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070915655
285 rdf:type schema:CreativeWork
286 https://www.grid.ac/institutes/grid.14848.31 schema:alternateName University of Montreal
287 schema:name Department of Pharmacology, Université de Montréal, H3T 1J4 Montréal, QC, Canada
288 rdf:type schema:Organization
289 https://www.grid.ac/institutes/grid.28046.38 schema:alternateName University of Ottawa
290 schema:name Centre for Advanced Research in Environmental Genomics, University of Ottawa, K1N6N5 Ottawa, ON, Canada
291 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...