Computational analysis of metabolic networks View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2008

AUTHORS

P.-Y. Bourguignon , J. van Helden , C. Ouzounis , V. Schächter

ABSTRACT

The metabolism of a species results from the joint operation of a large network of biochemical reactions, almost all of which are catalyzed by enzymes encoded in the genome of that species. Metabolic databases such as KEGG (Ogata et al. 1998; Kanehisa et al. 2006) or MetaCyc (Karp et al. 1996; Caspi et al. 2007) contain information about thousands of such reactions together with the compounds they involve. For instance, the KEGG database (as of January 2007) contains 6,580 reactions, and 5355 compounds, linked together by 13,490 substrate-to-reaction and 13,956 reaction-to-product relationships. In total, the KEGG database thus contains 18,515 entities (the metabolites and reactions), and 27,446 links (the substrate-to-reation and reaction-to-product-relationships). Furthermore, genes whose products are known to encode enzymes are linked to the corresponding reactions. More... »

PAGES

329-351

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-211-75123-7_16

DOI

http://dx.doi.org/10.1007/978-3-211-75123-7_16

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009941422


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