The skin as a model for the immunodulatory effects of corticotropin-releasing hormone View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2003

AUTHORS

Andrzej Slominski , Jacobo Wortsman , Elizabeth Linton , Alexander Pisarchik , Blazej Zbytek

ABSTRACT

The strategic location of the skin as the barrier between the environment and internal milieu determines its critical role in the preservation of body homeostasis [1].Thus, on the side facing the environment, the skin is continuously exposed to multiple noxious agents including the acute transfers of solar, thermal or mechanical energy. When these factors reach an intensity high enough to produce skin damage, several mechanisms rapidly come into play to restore the skin’s structural and functional integrity. Such mechanisms include the proliferative activity of the epidermis, the secretory activity of adnexal structures, and the activities of the pigmentary and the immune system, including its dermal vascular and mesenchymal components [1]. More... »

PAGES

149-176

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-0348-8039-8_10

DOI

http://dx.doi.org/10.1007/978-3-0348-8039-8_10

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019037033


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