Bacterial resistance to antibiotics: The role of biofilms View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1991

AUTHORS

John A. Salmon , Lawrence G. Garland , Brian D. Hoyle , J. William Costerton , Nikolaus Seiler , David Raeburn , Jan-Anders Karlsson , A. Polak , P. G. Hartman , Michel Rohmer , Philippe Bisseret , Bertrand Sutter , Alfred Burger

ABSTRACT

Bacteria adhere to natural and synthetic, medically important surfaces within an extracellular polymer generically termed the glycocalyx. This quasi-structure is a biofilm. The enhanced antibiotic resistance of biofilm bacteria, relative to floating (planktonic) bacteria, encourages the establishment of chronic bacterial infections. Resistance mechanisms include the hinderance of antibiotic diffusion by the glycocalyx, the physiology of the bacteria and the environment conditions of the niche in which the biofilm resides. More... »

PAGES

91-105

Book

TITLE

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques

ISBN

978-3-7643-2626-5
978-3-0348-7139-6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-0348-7139-6_2

DOI

http://dx.doi.org/10.1007/978-3-0348-7139-6_2

DIMENSIONS

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