Leukotriene antagonists and inhibitors of leukotriene biosynthesis as potential therapeutic agents View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1991

AUTHORS

John A. Salmon , Lawrence G. Garland , Brian D. Hoyle , J. William Costerton , Nikolaus Seiler , David Raeburn , Jan-Anders Karlsson , A. Polak , P. G. Hartman , Michel Rohmer , Philippe Bisseret , Bertrand Sutter , Alfred Burger

ABSTRACT

Arachidonic acid is converted by mammalian enzymes to a variety of oxygenated metabolites which include prostaglandins, thromboxanes and leukotrienes (collectively called eicosanoids). Many of these naturally occurring compounds have potent biological activities which suggest that they could be involved in mediating symptoms associated with various diseases (eg. allergic and inflammatory conditions). Thus, compounds which limit the effect of these mediators have therapeutic potential. More... »

PAGES

9-90

Book

TITLE

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques

ISBN

978-3-7643-2626-5
978-3-0348-7139-6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-3-0348-7139-6_1

DOI

http://dx.doi.org/10.1007/978-3-0348-7139-6_1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034701085


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