Cord Blood: A Massive Waste of a Life-Saving Resource, a Perspective on Its Current and Potential Uses View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2010-11-29

AUTHORS

Tang-Her Jaing , Robert Chow

ABSTRACT

Although allogeneic stem cell transplantation can cure patients with hematologic malignancies and nonmalignant disorders, limiting factors such as lack of suitable donors and graft-versus-host disease (GVHD) toxicity have led to the exploration of umbilical cord blood (UCB) as an alternative source of hematopoietic stem cells. The unique immunologic properties of UCB likely contribute to a decreased risk of GVHD. Thus, UCB represents a highly convenient hematopoietic stem cell (HSC) source that may significantly expand the HSC donor pool. Cord blood stem cells appear to confer significant advantages over adult stem cells, including ease of procurement, less of a requirement for human leukocyte antigen (HLA) matching, and fever side effects after use in transplant. Because of these characteristics, UCB is now the fastest growing source of stem cells for hematopoietic cell transplantation. More... »

PAGES

67-73

Book

TITLE

Regenerative Medicine Using Pregnancy-Specific Biological Substances

ISBN

978-1-84882-717-2
978-1-84882-718-9

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-84882-718-9_7

DOI

http://dx.doi.org/10.1007/978-1-84882-718-9_7

DIMENSIONS

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