The European Study Group for Pancreatic Cancer (ESPAC) Trials View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2009-12-02

AUTHORS

Paula Ghaneh , Khaled Dajani , Michael G. T. Raraty , Robert Suttton , John P. Neoptolemos

ABSTRACT

Pancreatic cancer is one of the most lethal malignancies with recent data quoting a worldwide annual incidence of 232,306 cases, resulting in 227,023 deaths (http://www-dep.iarc.fr/). In spite of the recent advances in the understanding of the biology, refined imaging systems, and improving surgical outcomes of pancreatic cancer, the overall 5-year survival for pancreatic cancer remains poor at less than 5% (Cress et al. 2006; Bramhall et al. 1995).Surgical resection remains the only potentially curative intervention. Due to late presentation, however, curative resections can be offered to only 10-15% of patients with pancreatic cancer (Alexakis et al. 2004) and confer only a median survival of 12-15 months (Shaib et al. 2007; Wagner et al. 2004). The aggressive biology of pancreatic cancer dictates that even following resection, the majority of patients experience tumor recurrence either locally or through distant metastases. More... »

PAGES

109-121

Book

TITLE

Pancreatic Disease

ISBN

978-1-84882-117-0
978-1-84882-118-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-84882-118-7_13

DOI

http://dx.doi.org/10.1007/978-1-84882-118-7_13

DIMENSIONS

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