Predicting RNA Structure: Advances and Limitations View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

Ivo L. Hofacker , Ronny Lorenz

ABSTRACT

RNA secondary structures can be predicted using efficient algorithms. A widely used software package implementing a large number of computational methods is the ViennaRNA Package. This chapter describes how to use programs from the ViennaRNA Package to perform common tasks such as prediction of minimum free-energy structures, suboptimal structures, or base pairing probabilities, and generating secondary structure plots with reliability annotation. Moreover, we present recent methods to assess the folding kinetics of an RNA via 2D projections of the energy landscape, identification of local minima and energy barriers, or simulation of RNA folding as a Markov process. More... »

PAGES

1-19

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-62703-667-2_1

DOI

http://dx.doi.org/10.1007/978-1-62703-667-2_1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049225975

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24136595


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