Ontology type: schema:Chapter
2013
AUTHORSEric D. Ross , Kyle S. MacLea , Charles Anderson , Asa Ben-Hur
ABSTRACTNumerous proteins contain domains that are enriched in glutamine and asparagine residues, and aggregation of some of these proteins has been linked to both prion formation in yeast and a number of human diseases. Unfortunately, predicting whether a given glutamine/asparagine-rich protein will aggregate has proven difficult. Here we describe a recently developed algorithm designed to predict the aggregation propensity of glutamine/asparagine-rich proteins. We discuss the basis for the algorithm, its limitations, and usage of recently developed online and downloadable versions of the algorithm. More... »
PAGES219-28
Tandem Repeats in Genes, Proteins, and Disease
ISBN
978-1-62703-437-1
978-1-62703-438-8
http://scigraph.springernature.com/pub.10.1007/978-1-62703-438-8_16
DOIhttp://dx.doi.org/10.1007/978-1-62703-438-8_16
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1025795158
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/23719919
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biochemistry and Cell Biology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Algorithms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Asparagine",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Computational Biology",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Glutamine",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Internet",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prions",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Protein Structure, Tertiary",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Saccharomyces cerevisiae",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sequence Analysis, Protein",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Software",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Colorado State University",
"id": "https://www.grid.ac/institutes/grid.47894.36",
"name": [
"Department of Biochemistry, Colorado State University, Fort Collins, CO, USA"
],
"type": "Organization"
},
"familyName": "Ross",
"givenName": "Eric D.",
"id": "sg:person.01241145525.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01241145525.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Colorado State University",
"id": "https://www.grid.ac/institutes/grid.47894.36",
"name": [
"Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA"
],
"type": "Organization"
},
"familyName": "MacLea",
"givenName": "Kyle S.",
"id": "sg:person.01055662734.77",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055662734.77"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Colorado State University",
"id": "https://www.grid.ac/institutes/grid.47894.36",
"name": [
"Department of Computer Science, Colorado State University, Fort Collins, CO, USA"
],
"type": "Organization"
},
"familyName": "Anderson",
"givenName": "Charles",
"id": "sg:person.0763303374.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763303374.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Colorado State University",
"id": "https://www.grid.ac/institutes/grid.47894.36",
"name": [
"Department of Computer Science, Colorado State University, Fort Collins, CO, USA"
],
"type": "Organization"
},
"familyName": "Ben-Hur",
"givenName": "Asa",
"id": "sg:person.01242755504.30",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01242755504.30"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/s1097-2765(00)80412-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001350463"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/bioinformatics/bti537",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004750770"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.1109434108",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008670436"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.1119366109",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009975995"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.brainres.2012.01.016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011889653"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.conb.2011.05.029",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017397796"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/gb-2003-4-6-r40",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019530303",
"https://doi.org/10.1186/gb-2003-4-6-r40"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/mcb.01140-09",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019653648"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/mcb.24.16.7206-7213.2004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023321443"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/hmg/dds116",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024890489"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0506136102",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025802652"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0506136102",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025802652"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.97.22.11910",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028520407"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cell.2009.02.044",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031198999"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1128/mcb.05338-11",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036118145"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/brain/awr201",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050508042"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1021/bi00699a001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1055185696"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/pri.17918",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072307023"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/pri.4.2.12190",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072307261"
],
"type": "CreativeWork"
}
],
"datePublished": "2013",
"datePublishedReg": "2013-01-01",
"description": "Numerous proteins contain domains that are enriched in glutamine and asparagine residues, and aggregation of some of these proteins has been linked to both prion formation in yeast and a number of human diseases. Unfortunately, predicting whether a given glutamine/asparagine-rich protein will aggregate has proven difficult. Here we describe a recently developed algorithm designed to predict the aggregation propensity of glutamine/asparagine-rich proteins. We discuss the basis for the algorithm, its limitations, and usage of recently developed online and downloadable versions of the algorithm.",
"editor": [
{
"familyName": "Hatters",
"givenName": "Danny M.",
"type": "Person"
},
{
"familyName": "Hannan",
"givenName": "Anthony J.",
"type": "Person"
}
],
"genre": "chapter",
"id": "sg:pub.10.1007/978-1-62703-438-8_16",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.3116644",
"type": "MonetaryGrant"
}
],
"isPartOf": {
"isbn": [
"978-1-62703-437-1",
"978-1-62703-438-8"
],
"name": "Tandem Repeats in Genes, Proteins, and Disease",
"type": "Book"
},
"name": "A Bioinformatics Method for Identifying Q/N-Rich Prion-Like Domains in Proteins",
"pagination": "219-28",
"productId": [
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/978-1-62703-438-8_16"
]
},
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"7ae491bfdf6b0eb18e7453559e52707cfbcd6033e173da316f945c3f30918111"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1025795158"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"23719919"
]
}
],
"publisher": {
"location": "Totowa, NJ",
"name": "Humana Press",
"type": "Organisation"
},
"sameAs": [
"https://doi.org/10.1007/978-1-62703-438-8_16",
"https://app.dimensions.ai/details/publication/pub.1025795158"
],
"sdDataset": "chapters",
"sdDatePublished": "2019-04-15T15:21",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000259.jsonl",
"type": "Chapter",
"url": "http://link.springer.com/10.1007/978-1-62703-438-8_16"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-62703-438-8_16'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-62703-438-8_16'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-62703-438-8_16'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-62703-438-8_16'
This table displays all metadata directly associated to this object as RDF triples.
198 TRIPLES
23 PREDICATES
57 URIs
32 LITERALS
20 BLANK NODES