Mosquito Transgenic Technologies to Reduce Plasmodium Transmission View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Silke Fuchs , Tony Nolan , Andrea Crisanti

ABSTRACT

The ability to introduce genetic constructs of choice into the genome of Anopheles mosquitoes provides a valuable tool to study the molecular interactions between the Plasmodium parasite and its insect host. In the long term, this technology could potentially offer new ways to control vector-borne diseases through the suppression of target mosquito populations or through the introgression of traits that preclude pathogen transmission. Here, we describe in detail protocols for the generation of transgenic Anopheles gambiae mosquitoes based on germ-line transformation using either modified transposable elements or the site-specific PhiC31 recombinase. More... »

PAGES

601-22

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-62703-026-7_41

DOI

http://dx.doi.org/10.1007/978-1-62703-026-7_41

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024565087

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22990807


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