Genetic Manipulation of Xanthophyllomyces dendrorhous and Phaffia rhodozyma View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Guangyun Lin , Joanna Bultman , Eric A. Johnson , Jack W. Fell

ABSTRACT

The yeasts Xanthophyllomyces dendrorhous (teleomorph) and Phaffia rhodozyma (anamorph) are of basidiomycetous affinity and have the unique property among yeasts of producing the carotenoid pigment astaxanthin. Astaxanthin imparts the attractive coloration to salmonids, crustaceans, and several birds such as the flamingo, and it has considerable economic value. Microbiological and genetic techniques for manipulation are rudimentary in the yeast, while their utility would be valuable for strain development including hypermutants that overproduce astaxanthin. Here we describe methods for manipulation of the yeast, including induction of the sexual stage with basidiospore formation, methods for isolation of mutants (particularly mutants affected in carotenoid biosynthesis) as well as techniques for isolation and analysis of carotenoids. These methods are valuable for understanding the biology and enhancing the biotechnology value of the yeast. More... »

PAGES

235-49

References to SciGraph publications

  • 1995. Microbial carotenoids in DOWNSTREAM PROCESSING BIOSURFACTANTS CAROTENOIDS
  • 2003-09. Phaffia rhodozyma: colorful odyssey in INTERNATIONAL MICROBIOLOGY
  • 1991-01. Isolation and Characterization of Carotenoid Hyperproducing Mutants of Yeast by Flow Cytometry and Cell Sorting in BIO/TECHNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-1-61779-918-1_16

    DOI

    http://dx.doi.org/10.1007/978-1-61779-918-1_16

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1012140082

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22711130


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