Peroxisome Targeting of Lycopene Pathway Enzymes in Pichia pastoris View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Pyung Cheon Lee

ABSTRACT

Cellular targeting of biosynthetic pathway enzymes is an invaluable technique in metabolic engineering to modify metabolic fluxes towards metabolite of interest. Especially, recombinant carotenoid biosynthesis in yeasts should be balanced with a precursor pathway present in a specific cellular location because yeasts, being eukaryotes, have more defined intracellular location. Here, peroxisomal targeting of lycopene pathway enzymes, CrtE, CrtB, and CrtI, by fusing to peroxisomal targeting sequence 1 (PTS1) in Pichia pastoris X-33 is described. More... »

PAGES

161-9

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-61779-918-1_10

DOI

http://dx.doi.org/10.1007/978-1-61779-918-1_10

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018777630

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22711124


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