Isolation of Adult Human Pluripotent Stem Cells from Mesenchymal Cell Populations and Their Application to Liver Damages View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Shohei Wakao , Masaaki Kitada , Yasumasa Kuroda , Mari Dezawa

ABSTRACT

We have found a novel type of pluripotent stem cells, Multilineage-differentiating stress enduring (Muse) cells that can be isolated from mesenchymal cell populations. Muse cells are characterized by stress tolerance, expression of pluripotency markers, self-renewal, and the ability to differentiate into endodermal-, mesodermal-, and ectodermal-lineage cells from a single cell, demonstrating that they are pluripotent stem cells. They can be isolated as cells positive for stage-specific embryonic antigen-3, a human pluripotent stem cell marker. Here, we introduce the isolation method for Muse cells and the effect of transplantation of these cells on chronic liver diseases. More... »

PAGES

89-102

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-61779-468-1_8

DOI

http://dx.doi.org/10.1007/978-1-61779-468-1_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009559424

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22167642


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