Cancer Stem Cells in Solid Tumors View Full Text


Ontology type: schema:Book     


Book Info

DATE

2011

GENRE

Book

AUTHORS

Hajime Hirose , Hirofumi Yamamoto , Norikatsu Miyoshi , Mamoru Uemura , Susumu Miyazaki , Hidekazu Takahashi , Ichiro Takemasa , Tsunekazu Mizushima , Masataka Ikeda , Hideshi Ishii , Mitsugu Sekimoto , Yuichiro Doki , Masaki Mori

PUBLISHER

Humana Press

ABSTRACT

In this review, we discuss recent issues about cancer stem cells, especially in solid tumors. Cancer stem cells show the ability to self-renew; and they possess multi-potential differentiation and tumorigenic potential. Cancer stem cells are reported to show resistance to anticancer drugs and radiotherapy, and therefore, they are involved in progression, recurrence, and metastasis in cancer. The existence of cancer stem cells in leukemia has long been known, since early times. In recent years cancer stem cells have been identified in solid tumors of breast, prostate, lung, brain, colon, and pancreas, owing to the development of identification techniques using cell surface markers. Although many features remain to be addressed, it is expected that cancer stem cells could be a main target for cancer therapy in the near future. More... »

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-61779-246-5

DOI

http://dx.doi.org/10.1007/978-1-61779-246-5

ISBN

978-1-61779-245-8 | 978-1-61779-246-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051314429

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21160254


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