Fluorescence Fluctuation Spectroscopy and Imaging Methods for Examination of Dynamic Protein Interactions in Yeast View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2011-07-15

AUTHORS

Brian D. Slaughter , Jay R. Unruh , Rong Li

ABSTRACT

Protein interactions are inherently dynamic. In no system is this more true and important than in signaling pathways, where spatial and temporal control of specific protein interactions is key to signaling specificity and timing. While genetic and biochemical interactions form a necessary and important starting point for deciphering interactions among signaling components, they struggle to provide precise information of where and when interactions occur in a live cell setting. In contrast, live cell fluorescence studies such as those outlined below are able to provide quantitative information on the strength, nature, timing, and location of homotypic and heterotypic protein interactions. More... »

PAGES

283-306

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-61779-173-4_17

DOI

http://dx.doi.org/10.1007/978-1-61779-173-4_17

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012556398

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21863494


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