Recipient Block TMA Technique View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2010-07-21

AUTHORS

Martina Mirlacher , Ronald Simon

ABSTRACT

New high-throughput screening technologies have led to the identification of hundreds of genes with a potential role in cancer or other diseases. One way to prioritize the leads obtained in such studies is to analyze a large number of tissues for candidate gene expression. The TMA methodology is now an established and frequently used tool for high-throughput tissue analysis. The recipient block technology is the "classical" method of TMA making. In this method, minute cylindrical tissue punches typically measuring 0.6 mm in diameter are removed from donor tissue blocks and are transferred into empty "recipient" paraffin blocks. Up to 1,000 different tissues can be analyzed in one TMA block. The equipment is affordable and easy to use in places where basic skills in histology are available. More... »

PAGES

37-44

Book

TITLE

Tissue Microarrays

ISBN

978-1-60761-805-8
978-1-60761-806-5

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-60761-806-5_4

DOI

http://dx.doi.org/10.1007/978-1-60761-806-5_4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017181165

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20690050


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