Visualisation of Lymphoid Organ Development View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2010

AUTHORS

Henrique Veiga-Fernandes , Katie Foster , Amisha Patel , Mark Coles , Dimitris Kioussis

ABSTRACT

This chapter provides information on imaging tools that can be employed to visualise and study lymphoid organ development. We focus on the use of genetically modified mouse models that take advantage of fluorescent protein expression in discrete cell populations, thus allowing live cell imaging during lymphoid organogenesis. We discuss approaches that allow characterisation of the cell types involved in the formation of lymphoid organs, including (i) functional assays in explant organ cultures and (ii) high-resolution whole-mount immunostaining methods, which are useful for the characterisation of specific cell populations in the context of the whole developing organ. More... »

PAGES

161-79

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-60761-461-6_11

DOI

http://dx.doi.org/10.1007/978-1-60761-461-6_11

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010405001

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20379875


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