Neuroendocrine and Metabolic Adaptations in the Central Nervous System That Facilitate Weight Regain View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2010-07-05

AUTHORS

Ronald M. Lechan , Csaba Fekete

ABSTRACT

Obesity is reaching epidemic proportions, yet short of surgical approaches, other modalities of treatment, in particular dietary restriction and behavioral modification, have been largely unsuccessful (1). At best, only ∼20% of overweight individuals are able to maintain at least a 10% weight reduction with diet for more than 1 year (2). The explanation for this largely dismal outlook is the remarkable nature of potent, compensatory, homeostatic systems in the brain that function to maintain body weight, uncoupling energy intake and output by increasing appetite, reducing energy expenditure, and promoting the hedonistic aspects of feeding behavior. More... »

PAGES

405-421

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  • Book

    TITLE

    Pediatric Obesity

    ISBN

    978-1-60327-873-7
    978-1-60327-874-4

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-1-60327-874-4_28

    DOI

    http://dx.doi.org/10.1007/978-1-60327-874-4_28

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1022528401


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