Proteomic Profiling of Human Brain Tumors View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2009

AUTHORS

Rongcai Jiang , Jian Yi Li , Gregory N. Fuller , Wei Zhang

ABSTRACT

Although challenging, proteomic profiling has recently become a hot area in cancer research, and a majority of the currently available methodologies, such as two-dimensional polyacrylamide gel electrophoresis, two-dimensional difference gel electrophoresis, liquid chromatography, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, surface-enhanced laser desorption/ionization time-of-flight MS, tissue microarrays, and protein and antibody arrays, have been used in human brain tumor research. These studies have generated an enormous amount of data, and, in the postproteomics era, more powerful bioinformatics tools are needed to effectively mine proteomics data efficiently and accurately. The design, execution, and interpretation of in vitro and in vivo biological confirmatory experiments constitute major tasks for scientists who seek to identify clinically meaningful diagnostic and prognostic makers. More... »

PAGES

553-575

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-60327-553-8_24

DOI

http://dx.doi.org/10.1007/978-1-60327-553-8_24

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010588273


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