Techno-Economic Analysis of Biocatalytic Processes for Production of Alkene Epoxides View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2007

AUTHORS

Abhijeet P. Borole , Brian H. Davison

ABSTRACT

A techno-economic analysis of two different bioprocesses was conducted, one for the conversion of propylene to propylene oxide (PO) and other for conversion of styrene to styrene epoxide (SO). The first process was a lipasemediated chemo-enzymatic reaction, whereas the second one was a one-step enzymatic process using chloroperoxidase. The PO produced through the chemo-enzymatic process is a racemic product, whereas the latter process (based on chloroperoxidase) produces an enantio-pure product. The former process thus falls under the category of high-volume commodity chemical (PO); whereas the latter is a low-volume, high-value product (SO). A simulation of the process was conducted using the bioprocess engineering software SuperPro Designer v6.0 (Intelligen, Inc., Scotch Plains, NJ) to determine the economic feasibility of the process. The purpose of the exercise was to compare biocatalytic processes with existing chemical processes for production of alkene expoxides. The results show that further improvements are needed in improving biocatalyst stability to make these bioprocesses competitive with chemical processes. More... »

PAGES

437-449

Book

TITLE

Applied Biochemistry and Biotecnology

ISBN

978-1-60327-180-6
978-1-60327-181-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-60327-181-3_37

DOI

http://dx.doi.org/10.1007/978-1-60327-181-3_37

DIMENSIONS

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