Molecularly Targeted Therapy in Pancreatic Cancer View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2008

AUTHORS

Anupama Goel , Peter Kozuch

ABSTRACT

Pancreatic cancer is predicted to remain as the fourth leading cause of cancer associated death in the United States in 2006. The annual death rate approximates the annual incidence rate because this disease, with rare exception, becomes locally advanced or metastatic and resistant to cytotoxic chemotherapy. Unfortunately, in eight randomized controlled clinical trials, the standard oncologic principle of combining drugs with demonstrated single agent activity and unique mechanism of action has not resulted in clinical benefit beyond gemcitabine alone. Molecular pathways that confer significant biological advantage to most human cancers have been identified over the past three decades. Drugs designed to specifically disrupt these essential pathways are currently in clinical development and hopefully will bear new standards of care for patients with pancreatic cancer. More... »

PAGES

211-226

References to SciGraph publications

Book

TITLE

Molecular Targeting in Oncology

ISBN

978-1-58829-577-4
978-1-59745-337-0

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-59745-337-0_9

DOI

http://dx.doi.org/10.1007/978-1-59745-337-0_9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003023706


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-59745-337-0_9'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-59745-337-0_9'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-59745-337-0_9'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-59745-337-0_9'


 

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