Production and Characterization of Immortal Human Neural Stem Cell Line with Multipotent Differentiation Property View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2008

AUTHORS

Seung U. Kim , Atsushi Nagai , Eiji Nakagawa , Hyun B. Choi , Jung H. Bang , Hong J. Lee , Myung A. Lee , Yong B. Lee , In H. Park

ABSTRACT

We document the protocols and methods for the production of immortalized cell lines of human neural stem cells from the human fetal central nervous system (CNS) cells by using a retroviral vector encoding v-myc oncogene. One of the human neural stem cell lines (HB1.F3) was found to express nestin and other specific markers for human neural stem cells, giving rise to three fundamental cell types of the CNS: neurons, astrocytes, and oligodendrocytes. After transplantation into the brain of mouse model of stroke, implanted human neural stem cells were observed to migrate extensively from the site of implantation into other anatomical sites and to differentiate into neurons and glial cells. More... »

PAGES

103-121

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-59745-133-8_10

DOI

http://dx.doi.org/10.1007/978-1-59745-133-8_10

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022454904

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18369753


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

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N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-59745-133-8_10'


 

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