Scoring Functions for Mass Spectrometric Protein Identification View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2003

AUTHORS

Robin Gras , Patricia Hernandez , Markus Müller , Ron D. Appel

ABSTRACT

The new reliability and availability of mass spectrometric instruments and of protein separation techniques associated with complete sequencing of several hundred genomes (http://www.ebi.ac.uk/genomes) allow us to carry out large gene and protein expression studies (proteomics) (1,2). The need to produce, manage, and analyze a huge amount of data calls for the application of specific biological and bioinformatics techniques. A complete protein project is built in several steps. Proteins must be purified to make analysis by mass spectrometry (MS) feasible. Then the spectra must be analyzed, providing a list of peptide masses in the case of peptide mass fingerprinting (PMF spectra or MS spectra) or peptide fragment masses in the case of MS/MS spectra. More... »

PAGES

477-485

Book

TITLE

Handbook of Proteomic Methods

ISBN

978-1-61737-504-0
978-1-59259-414-6

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-59259-414-6_34

DOI

http://dx.doi.org/10.1007/978-1-59259-414-6_34

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022246010


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