Toxoplasma gondii as a Model of In Vivo Host-Parasite Interactions. View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2019

AUTHORS

Sheryl Coutermarsh-Ott

ABSTRACT

Toxoplasma gondii is an intracellular, apicomplexan parasite of great importance in both human and animal health. Current research has identified a variety of important and necessary factors specific to the parasite that enable it to infect and persist in a wide array of mammalian hosts. However, in order to continue to build our understanding of T. gondii pathogenesis, the relevance of these parasite characteristics needs continued investigation in animal models. In the following chapter, we present a model of intraperitoneal infection of C57BL/6 mice with T. gondii tachyzoites that, in C57BL/6 mice, elicits a strong acute immune response. Moreover, we present methods for sampling and analyzing peritoneal and bronchoalveolar lavage fluids in order to assess localized and systemic immune reactions to the parasite. More... »

PAGES

237-247

Book

TITLE

Mouse Models of Innate Immunity

ISBN

978-1-4939-9166-2
978-1-4939-9167-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-9167-9_21

DOI

http://dx.doi.org/10.1007/978-1-4939-9167-9_21

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112367018

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30798537


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