Computational Analysis of Protein-Protein Interactions in Motile T-Cells. View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2019

AUTHORS

Sunil Kumar , Mobashar Hussain Urf Turabe Fazil , Khurshid Ahmad , Minaketan Tripathy , Jagath Chandana Rajapakse , Navin Kumar Verma

ABSTRACT

Analysis of protein-protein interactions is important for better understanding of molecular mechanisms involved in immune regulation and has potential for elaborating avenues for drug discovery targeting T-cell motility. Currently, only a small fraction of protein-protein interactions have been characterized in T-lymphocytes although there are several detection methods available. In this regard, computational approaches garner importance, with the continued explosion of genomic and proteomic data, for handling protein modeling and protein-protein interactions in large scale. Here, we describe a computational method to identify protein-protein interactions based on in silico protein design. More... »

PAGES

149-156

Book

TITLE

T-Cell Motility

ISBN

978-1-4939-9035-1
978-1-4939-9036-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-9036-8_18

DOI

http://dx.doi.org/10.1007/978-1-4939-9036-8_18

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111099907

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30610609


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Life Sciences", 
          "id": "https://www.grid.ac/institutes/grid.418782.0", 
          "name": [
            "ICAR-NBAIM, Mau, Uttar Pradesh, India. skybiotech@gmail.com.", 
            "Institute of Life Sciences, Bhubaneswar, Odisha, India. skybiotech@gmail.com."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumar", 
        "givenName": "Sunil", 
        "id": "sg:person.01040121423.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040121423.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nanyang Technological University", 
          "id": "https://www.grid.ac/institutes/grid.59025.3b", 
          "name": [
            "Lymphocyte Signalling Research Laboratory, Lee Kong Chain School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fazil", 
        "givenName": "Mobashar Hussain Urf Turabe", 
        "id": "sg:person.01210703427.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210703427.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "ICAR-NBAIM, Mau, Uttar Pradesh, India."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ahmad", 
        "givenName": "Khurshid", 
        "id": "sg:person.01033023112.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033023112.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Universiti Teknologi MARA", 
          "id": "https://www.grid.ac/institutes/grid.412259.9", 
          "name": [
            "Laboratory of Fundamentals of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tripathy", 
        "givenName": "Minaketan", 
        "id": "sg:person.01317737263.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317737263.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nanyang Technological University", 
          "id": "https://www.grid.ac/institutes/grid.59025.3b", 
          "name": [
            "School of Computer Science and Engineering, Nanyang Technological University Singapore, Singapore, Singapore."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rajapakse", 
        "givenName": "Jagath Chandana", 
        "id": "sg:person.0713022574.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713022574.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nanyang Technological University", 
          "id": "https://www.grid.ac/institutes/grid.59025.3b", 
          "name": [
            "Lee Kong Chain School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Verma", 
        "givenName": "Navin Kumar", 
        "id": "sg:person.01067216241.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067216241.35"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.imlet.2005.06.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004246132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cellsig.2013.04.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008276363"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10482-014-0308-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021743522", 
          "https://doi.org/10.1007/s10482-014-0308-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10482-014-0308-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021743522", 
          "https://doi.org/10.1007/s10482-014-0308-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.softx.2015.06.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028157022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1993.1626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030443070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00894-010-0947-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053523490", 
          "https://doi.org/10.1007/s00894-010-0947-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1501264", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079273730"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1700495", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091089347"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2018.02.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100960554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2018.02.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100960554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2018.02.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100960554"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019", 
    "datePublishedReg": "2019-01-01", 
    "description": "Analysis of protein-protein interactions is important for better understanding of molecular mechanisms involved in immune regulation and has potential for elaborating avenues for drug discovery targeting T-cell motility. Currently, only a small fraction of protein-protein interactions have been characterized in T-lymphocytes although there are several detection methods available. In this regard, computational approaches garner importance, with the continued explosion of genomic and proteomic data, for handling protein modeling and protein-protein interactions in large scale. Here, we describe a computational method to identify protein-protein interactions based on in silico protein design.", 
    "editor": [
      {
        "familyName": "Verma", 
        "givenName": "Navin Kumar", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4939-9036-8_18", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4939-9035-1", 
        "978-1-4939-9036-8"
      ], 
      "name": "T-Cell Motility", 
      "type": "Book"
    }, 
    "name": "Computational Analysis of Protein-Protein Interactions in Motile T-Cells.", 
    "pagination": "149-156", 
    "productId": [
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30610609"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1111099907"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4939-9036-8_18"
        ]
      }
    ], 
    "publisher": {
      "location": "New York, NY", 
      "name": "Springer New York", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4939-9036-8_18", 
      "https://app.dimensions.ai/details/publication/pub.1111099907"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-16T07:46", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000358_0000000358/records_127435_00000011.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4939-9036-8_18"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-9036-8_18'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-9036-8_18'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-9036-8_18'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-9036-8_18'


 

This table displays all metadata directly associated to this object as RDF triples.

140 TRIPLES      23 PREDICATES      36 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4939-9036-8_18 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author Na656af7b02244d33b432d628e7888194
4 schema:citation sg:pub.10.1007/s00894-010-0947-6
5 sg:pub.10.1007/s10482-014-0308-z
6 https://doi.org/10.1006/jmbi.1993.1626
7 https://doi.org/10.1016/j.cellsig.2013.04.002
8 https://doi.org/10.1016/j.imlet.2005.06.014
9 https://doi.org/10.1016/j.pep.2018.02.002
10 https://doi.org/10.1016/j.softx.2015.06.001
11 https://doi.org/10.4049/jimmunol.1501264
12 https://doi.org/10.4049/jimmunol.1700495
13 schema:datePublished 2019
14 schema:datePublishedReg 2019-01-01
15 schema:description Analysis of protein-protein interactions is important for better understanding of molecular mechanisms involved in immune regulation and has potential for elaborating avenues for drug discovery targeting T-cell motility. Currently, only a small fraction of protein-protein interactions have been characterized in T-lymphocytes although there are several detection methods available. In this regard, computational approaches garner importance, with the continued explosion of genomic and proteomic data, for handling protein modeling and protein-protein interactions in large scale. Here, we describe a computational method to identify protein-protein interactions based on in silico protein design.
16 schema:editor N94849e04baa24bf58e248b9c20bfb0de
17 schema:genre chapter
18 schema:inLanguage en
19 schema:isAccessibleForFree false
20 schema:isPartOf N3188f5c611c94fdabc7e9b88afb4c0da
21 schema:name Computational Analysis of Protein-Protein Interactions in Motile T-Cells.
22 schema:pagination 149-156
23 schema:productId N73780b34832c40c697c6de5d28349bc8
24 Nb1fb63afb6f4484791756cf1a4535836
25 Nef180dcc42c8485381c2a84bffba17c3
26 schema:publisher N9495c7763708498c9b6ca8cdefa54f4a
27 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111099907
28 https://doi.org/10.1007/978-1-4939-9036-8_18
29 schema:sdDatePublished 2019-04-16T07:46
30 schema:sdLicense https://scigraph.springernature.com/explorer/license/
31 schema:sdPublisher Nd9db74fffc9d47849d77a8289087fe65
32 schema:url http://link.springer.com/10.1007/978-1-4939-9036-8_18
33 sgo:license sg:explorer/license/
34 sgo:sdDataset chapters
35 rdf:type schema:Chapter
36 N1e80dfa8f4754af28d76fcbf5b0b8347 rdf:first sg:person.01317737263.25
37 rdf:rest Nc542dfe859dc484abfd6d85887e591d1
38 N2b64dd226efd42ba8ca0d195916c9e09 schema:familyName Verma
39 schema:givenName Navin Kumar
40 rdf:type schema:Person
41 N3188f5c611c94fdabc7e9b88afb4c0da schema:isbn 978-1-4939-9035-1
42 978-1-4939-9036-8
43 schema:name T-Cell Motility
44 rdf:type schema:Book
45 N46d218798142407982366037588f5dcc schema:name ICAR-NBAIM, Mau, Uttar Pradesh, India.
46 rdf:type schema:Organization
47 N6c0a811685ca4362847389e4c624ec45 rdf:first sg:person.01210703427.59
48 rdf:rest Nc7da2b6970f74833aa1afcdbeb68670f
49 N73780b34832c40c697c6de5d28349bc8 schema:name pubmed_id
50 schema:value 30610609
51 rdf:type schema:PropertyValue
52 N94849e04baa24bf58e248b9c20bfb0de rdf:first N2b64dd226efd42ba8ca0d195916c9e09
53 rdf:rest rdf:nil
54 N9495c7763708498c9b6ca8cdefa54f4a schema:location New York, NY
55 schema:name Springer New York
56 rdf:type schema:Organisation
57 Na656af7b02244d33b432d628e7888194 rdf:first sg:person.01040121423.50
58 rdf:rest N6c0a811685ca4362847389e4c624ec45
59 Nb1fb63afb6f4484791756cf1a4535836 schema:name doi
60 schema:value 10.1007/978-1-4939-9036-8_18
61 rdf:type schema:PropertyValue
62 Nc542dfe859dc484abfd6d85887e591d1 rdf:first sg:person.0713022574.39
63 rdf:rest Ndb639b61504e415aa609fe0cfcc5959a
64 Nc7da2b6970f74833aa1afcdbeb68670f rdf:first sg:person.01033023112.33
65 rdf:rest N1e80dfa8f4754af28d76fcbf5b0b8347
66 Nd9db74fffc9d47849d77a8289087fe65 schema:name Springer Nature - SN SciGraph project
67 rdf:type schema:Organization
68 Ndb639b61504e415aa609fe0cfcc5959a rdf:first sg:person.01067216241.35
69 rdf:rest rdf:nil
70 Nef180dcc42c8485381c2a84bffba17c3 schema:name dimensions_id
71 schema:value pub.1111099907
72 rdf:type schema:PropertyValue
73 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
74 schema:name Biological Sciences
75 rdf:type schema:DefinedTerm
76 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
77 schema:name Biochemistry and Cell Biology
78 rdf:type schema:DefinedTerm
79 sg:person.01033023112.33 schema:affiliation N46d218798142407982366037588f5dcc
80 schema:familyName Ahmad
81 schema:givenName Khurshid
82 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033023112.33
83 rdf:type schema:Person
84 sg:person.01040121423.50 schema:affiliation https://www.grid.ac/institutes/grid.418782.0
85 schema:familyName Kumar
86 schema:givenName Sunil
87 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01040121423.50
88 rdf:type schema:Person
89 sg:person.01067216241.35 schema:affiliation https://www.grid.ac/institutes/grid.59025.3b
90 schema:familyName Verma
91 schema:givenName Navin Kumar
92 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067216241.35
93 rdf:type schema:Person
94 sg:person.01210703427.59 schema:affiliation https://www.grid.ac/institutes/grid.59025.3b
95 schema:familyName Fazil
96 schema:givenName Mobashar Hussain Urf Turabe
97 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210703427.59
98 rdf:type schema:Person
99 sg:person.01317737263.25 schema:affiliation https://www.grid.ac/institutes/grid.412259.9
100 schema:familyName Tripathy
101 schema:givenName Minaketan
102 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317737263.25
103 rdf:type schema:Person
104 sg:person.0713022574.39 schema:affiliation https://www.grid.ac/institutes/grid.59025.3b
105 schema:familyName Rajapakse
106 schema:givenName Jagath Chandana
107 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713022574.39
108 rdf:type schema:Person
109 sg:pub.10.1007/s00894-010-0947-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053523490
110 https://doi.org/10.1007/s00894-010-0947-6
111 rdf:type schema:CreativeWork
112 sg:pub.10.1007/s10482-014-0308-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1021743522
113 https://doi.org/10.1007/s10482-014-0308-z
114 rdf:type schema:CreativeWork
115 https://doi.org/10.1006/jmbi.1993.1626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030443070
116 rdf:type schema:CreativeWork
117 https://doi.org/10.1016/j.cellsig.2013.04.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008276363
118 rdf:type schema:CreativeWork
119 https://doi.org/10.1016/j.imlet.2005.06.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004246132
120 rdf:type schema:CreativeWork
121 https://doi.org/10.1016/j.pep.2018.02.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100960554
122 rdf:type schema:CreativeWork
123 https://doi.org/10.1016/j.softx.2015.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028157022
124 rdf:type schema:CreativeWork
125 https://doi.org/10.4049/jimmunol.1501264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079273730
126 rdf:type schema:CreativeWork
127 https://doi.org/10.4049/jimmunol.1700495 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091089347
128 rdf:type schema:CreativeWork
129 https://www.grid.ac/institutes/grid.412259.9 schema:alternateName Universiti Teknologi MARA
130 schema:name Laboratory of Fundamentals of Pharmaceutics, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bandar Puncak Alam, Selangor, Malaysia.
131 rdf:type schema:Organization
132 https://www.grid.ac/institutes/grid.418782.0 schema:alternateName Institute of Life Sciences
133 schema:name ICAR-NBAIM, Mau, Uttar Pradesh, India. skybiotech@gmail.com.
134 Institute of Life Sciences, Bhubaneswar, Odisha, India. skybiotech@gmail.com.
135 rdf:type schema:Organization
136 https://www.grid.ac/institutes/grid.59025.3b schema:alternateName Nanyang Technological University
137 schema:name Lee Kong Chain School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
138 Lymphocyte Signalling Research Laboratory, Lee Kong Chain School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.
139 School of Computer Science and Engineering, Nanyang Technological University Singapore, Singapore, Singapore.
140 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...