Monitoring the Transcriptional Activity of FOXO Transcription Factors by Analyzing their Target Genes View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2018-11-10

AUTHORS

Vanessa Henriques , Susana Machado , Wolfgang Link , Bibiana I. Ferreira

ABSTRACT

FOXO proteins represent a subfamily of transcription factors that belong to the forkhead family. The study of FOXO target genes can be performed using Real-Time PCR (RT-PCR). The RT-PCR is a sensitive method that allows the detection and quantification of minute amounts of nucleic acids. In RT-PCR the accumulation of the amplicon is detected and measured as the reaction progresses. Here, we describe the application of RT-PCR technique to monitor the transcriptional activity of FOXO transcription factors. More... »

PAGES

103-113

Book

TITLE

FOXO Transcription Factors

ISBN

978-1-4939-8899-0
978-1-4939-8900-3

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-8900-3_9

DOI

http://dx.doi.org/10.1007/978-1-4939-8900-3_9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1109830106

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30414148


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