Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity. View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2019

AUTHORS

Alba Orea-Soufi , David Dávila , María Salazar-Roa , María de Mar Lorente , Guillermo Velasco

ABSTRACT

Phosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulation of the activity, nucleo-cytosolic shuttling, and stability of this family of proteins. Here, we describe several experimental approaches allowing analysis of changes in the phosphorylation of these proteins upon exposure to different stimuli.

PAGES

51-59

Book

TITLE

FOXO Transcription Factors

ISBN

978-1-4939-8899-0
978-1-4939-8900-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-8900-3_5

DOI

http://dx.doi.org/10.1007/978-1-4939-8900-3_5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1109830102

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30414144


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Complutense University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.4795.f", 
          "name": [
            "Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.", 
            "Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Orea-Soufi", 
        "givenName": "Alba", 
        "id": "sg:person.01014217425.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014217425.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complutense University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.4795.f", 
          "name": [
            "Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.", 
            "Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "D\u00e1vila", 
        "givenName": "David", 
        "id": "sg:person.01341761602.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341761602.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complutense University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.4795.f", 
          "name": [
            "Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.", 
            "Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Salazar-Roa", 
        "givenName": "Mar\u00eda", 
        "id": "sg:person.01251325250.85", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251325250.85"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complutense University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.4795.f", 
          "name": [
            "Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.", 
            "Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain."
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Mar Lorente", 
        "givenName": "Mar\u00eda", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complutense University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.4795.f", 
          "name": [
            "Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain. gvelasco@ucm.es.", 
            "Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain. gvelasco@ucm.es."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Velasco", 
        "givenName": "Guillermo", 
        "id": "sg:person.010133063660.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010133063660.50"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.cub.2007.08.047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000866349"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-60327-115-8_13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006169042", 
          "https://doi.org/10.1007/978-1-60327-115-8_13"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-60327-115-8_13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006169042", 
          "https://doi.org/10.1007/978-1-60327-115-8_13"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2006.03.046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020133557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m111.284224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025655045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1676", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029052135", 
          "https://doi.org/10.1038/ncb1676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tcb.2008.07.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031569784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)80595-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032865792"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cdd.2014.133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044562702", 
          "https://doi.org/10.1038/cdd.2014.133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cdd.2012.49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051857275", 
          "https://doi.org/10.1038/cdd.2012.49"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019", 
    "datePublishedReg": "2019-01-01", 
    "description": "Phosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulation of the activity, nucleo-cytosolic shuttling, and stability of this family of proteins. Here, we describe several experimental approaches allowing analysis of changes in the phosphorylation of these proteins upon exposure to different stimuli.", 
    "editor": [
      {
        "familyName": "Link", 
        "givenName": "Wolfgang", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4939-8900-3_5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4939-8899-0", 
        "978-1-4939-8900-3"
      ], 
      "name": "FOXO Transcription Factors", 
      "type": "Book"
    }, 
    "name": "Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity.", 
    "pagination": "51-59", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4939-8900-3_5"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1109830102"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30414144"
        ]
      }
    ], 
    "publisher": {
      "location": "New York, NY", 
      "name": "Springer New York", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4939-8900-3_5", 
      "https://app.dimensions.ai/details/publication/pub.1109830102"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-16T05:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000339_0000000339/records_109513_00000002.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4939-8900-3_5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-8900-3_5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-8900-3_5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-8900-3_5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-8900-3_5'


 

This table displays all metadata directly associated to this object as RDF triples.

126 TRIPLES      23 PREDICATES      36 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4939-8900-3_5 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N1fc841465c9d4565967cb51a47b7d864
4 schema:citation sg:pub.10.1007/978-1-60327-115-8_13
5 sg:pub.10.1038/cdd.2012.49
6 sg:pub.10.1038/cdd.2014.133
7 sg:pub.10.1038/ncb1676
8 https://doi.org/10.1016/j.cell.2006.03.046
9 https://doi.org/10.1016/j.cub.2007.08.047
10 https://doi.org/10.1016/j.tcb.2008.07.004
11 https://doi.org/10.1016/s0092-8674(00)80595-4
12 https://doi.org/10.1074/jbc.m111.284224
13 schema:datePublished 2019
14 schema:datePublishedReg 2019-01-01
15 schema:description Phosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulation of the activity, nucleo-cytosolic shuttling, and stability of this family of proteins. Here, we describe several experimental approaches allowing analysis of changes in the phosphorylation of these proteins upon exposure to different stimuli.
16 schema:editor N61aad83dad9f49dc8ec7af7c1aae019d
17 schema:genre chapter
18 schema:inLanguage en
19 schema:isAccessibleForFree false
20 schema:isPartOf N404c2596d87f4c208cfb0d0ab8cce209
21 schema:name Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity.
22 schema:pagination 51-59
23 schema:productId N1ac9b28c98ca4d3eb54697621176fa18
24 N3e164bfa40704b599723cb9796135661
25 Nd8dd694f6b654e77a45983fc1a3076cb
26 schema:publisher N619c6869bc534d4b97a420475e020b72
27 schema:sameAs https://app.dimensions.ai/details/publication/pub.1109830102
28 https://doi.org/10.1007/978-1-4939-8900-3_5
29 schema:sdDatePublished 2019-04-16T05:22
30 schema:sdLicense https://scigraph.springernature.com/explorer/license/
31 schema:sdPublisher Ne3f52b2348cd48c7a533fabd974744c2
32 schema:url http://link.springer.com/10.1007/978-1-4939-8900-3_5
33 sgo:license sg:explorer/license/
34 sgo:sdDataset chapters
35 rdf:type schema:Chapter
36 N1ac9b28c98ca4d3eb54697621176fa18 schema:name pubmed_id
37 schema:value 30414144
38 rdf:type schema:PropertyValue
39 N1fc841465c9d4565967cb51a47b7d864 rdf:first sg:person.01014217425.07
40 rdf:rest N22b4dd0ed74a4ff7a91b2bd918737187
41 N22b4dd0ed74a4ff7a91b2bd918737187 rdf:first sg:person.01341761602.37
42 rdf:rest N58aa586ea6074ef1943bb99422a8f1bd
43 N27b471450283458998ccc75bed8ea22c rdf:first sg:person.010133063660.50
44 rdf:rest rdf:nil
45 N3e164bfa40704b599723cb9796135661 schema:name doi
46 schema:value 10.1007/978-1-4939-8900-3_5
47 rdf:type schema:PropertyValue
48 N404c2596d87f4c208cfb0d0ab8cce209 schema:isbn 978-1-4939-8899-0
49 978-1-4939-8900-3
50 schema:name FOXO Transcription Factors
51 rdf:type schema:Book
52 N58aa586ea6074ef1943bb99422a8f1bd rdf:first sg:person.01251325250.85
53 rdf:rest Nca729d8b928d45f98961660bad74b8ef
54 N619c6869bc534d4b97a420475e020b72 schema:location New York, NY
55 schema:name Springer New York
56 rdf:type schema:Organisation
57 N61aad83dad9f49dc8ec7af7c1aae019d rdf:first Na0b8b5109d174bd3b1c49cd90ccc1a63
58 rdf:rest rdf:nil
59 Na0b8b5109d174bd3b1c49cd90ccc1a63 schema:familyName Link
60 schema:givenName Wolfgang
61 rdf:type schema:Person
62 Nca729d8b928d45f98961660bad74b8ef rdf:first Nf545665713224f4fad9e3e86a6d1aad6
63 rdf:rest N27b471450283458998ccc75bed8ea22c
64 Nd8dd694f6b654e77a45983fc1a3076cb schema:name dimensions_id
65 schema:value pub.1109830102
66 rdf:type schema:PropertyValue
67 Ne3f52b2348cd48c7a533fabd974744c2 schema:name Springer Nature - SN SciGraph project
68 rdf:type schema:Organization
69 Nf545665713224f4fad9e3e86a6d1aad6 schema:affiliation https://www.grid.ac/institutes/grid.4795.f
70 schema:familyName de Mar Lorente
71 schema:givenName María
72 rdf:type schema:Person
73 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
74 schema:name Biological Sciences
75 rdf:type schema:DefinedTerm
76 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
77 schema:name Biochemistry and Cell Biology
78 rdf:type schema:DefinedTerm
79 sg:person.010133063660.50 schema:affiliation https://www.grid.ac/institutes/grid.4795.f
80 schema:familyName Velasco
81 schema:givenName Guillermo
82 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010133063660.50
83 rdf:type schema:Person
84 sg:person.01014217425.07 schema:affiliation https://www.grid.ac/institutes/grid.4795.f
85 schema:familyName Orea-Soufi
86 schema:givenName Alba
87 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014217425.07
88 rdf:type schema:Person
89 sg:person.01251325250.85 schema:affiliation https://www.grid.ac/institutes/grid.4795.f
90 schema:familyName Salazar-Roa
91 schema:givenName María
92 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251325250.85
93 rdf:type schema:Person
94 sg:person.01341761602.37 schema:affiliation https://www.grid.ac/institutes/grid.4795.f
95 schema:familyName Dávila
96 schema:givenName David
97 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341761602.37
98 rdf:type schema:Person
99 sg:pub.10.1007/978-1-60327-115-8_13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006169042
100 https://doi.org/10.1007/978-1-60327-115-8_13
101 rdf:type schema:CreativeWork
102 sg:pub.10.1038/cdd.2012.49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051857275
103 https://doi.org/10.1038/cdd.2012.49
104 rdf:type schema:CreativeWork
105 sg:pub.10.1038/cdd.2014.133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044562702
106 https://doi.org/10.1038/cdd.2014.133
107 rdf:type schema:CreativeWork
108 sg:pub.10.1038/ncb1676 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029052135
109 https://doi.org/10.1038/ncb1676
110 rdf:type schema:CreativeWork
111 https://doi.org/10.1016/j.cell.2006.03.046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020133557
112 rdf:type schema:CreativeWork
113 https://doi.org/10.1016/j.cub.2007.08.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000866349
114 rdf:type schema:CreativeWork
115 https://doi.org/10.1016/j.tcb.2008.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031569784
116 rdf:type schema:CreativeWork
117 https://doi.org/10.1016/s0092-8674(00)80595-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032865792
118 rdf:type schema:CreativeWork
119 https://doi.org/10.1074/jbc.m111.284224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025655045
120 rdf:type schema:CreativeWork
121 https://www.grid.ac/institutes/grid.4795.f schema:alternateName Complutense University of Madrid
122 schema:name Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.
123 Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain. gvelasco@ucm.es.
124 Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain.
125 Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Madrid, Spain. gvelasco@ucm.es.
126 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...