Elastase-Induced Lung Emphysema Models in Mice View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2017

AUTHORS

Béla Suki , Erzsébet Bartolák-Suki , Patricia R. M. Rocco

ABSTRACT

Pulmonary emphysema is one of the distinct pathological forms of chronic obstructive pulmonary disease (COPD) that is accompanied by gradual elimination of alveolar tissue, causing reductions in lung recoil and leading to difficulty in breathing. As there is no cure for emphysema, animal models are often used to better understand the pathogenesis and progression of the disease. One widely used animal model of emphysema is the elastase treatment. In this chapter, we describe two methods of elastase-induced emphysema in mice. The first is a single-dose treatment, whereby elastase is introduced oropharengeally into the lung and the structure and/or function of the lungs are studied between 2 days and 4 weeks following the treatment. The second method consists of exposing mice repeatedly (four times) to elastase intratracheally and observing the effects of the treatment 1-4 weeks following the last administration of the enzyme. Both protocols are described in detail, and examples of lung structure and function of the emphysematous mouse lung are provided. More... »

PAGES

67-75

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-7163-3_7

DOI

http://dx.doi.org/10.1007/978-1-4939-7163-3_7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1090910130

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28752447


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Collagen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Models, Animal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred BALB C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred C57BL", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pancreatic Elastase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pulmonary Emphysema", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sus scrofa", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Boston University", 
          "id": "https://www.grid.ac/institutes/grid.189504.1", 
          "name": [
            "Boston University"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suki", 
        "givenName": "B\u00e9la", 
        "id": "sg:person.0730323706.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730323706.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Boston University", 
          "id": "https://www.grid.ac/institutes/grid.189504.1", 
          "name": [
            "Boston University"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bartol\u00e1k-Suki", 
        "givenName": "Erzs\u00e9bet", 
        "id": "sg:person.010506062527.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010506062527.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Federal University of Rio de Janeiro", 
          "id": "https://www.grid.ac/institutes/grid.8536.8", 
          "name": [
            "Federal University of Rio de Janeiro"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rocco", 
        "givenName": "Patricia R. M.", 
        "id": "sg:person.012174761157.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012174761157.42"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1165/rcmb.2010-0473oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000162327"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pmed.0030442", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002063116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4800(92)90033-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004367015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00424.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013894166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01902140590918669", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014743019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thorax.2003.006494", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018312000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/thorax.2003.006494", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018312000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12931-014-0118-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021154228", 
          "https://doi.org/10.1186/s12931-014-0118-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12931-014-0118-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021154228", 
          "https://doi.org/10.1186/s12931-014-0118-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1007625107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021244161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1165/rcmb.2008-0424oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021776128"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00590.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022223453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1165/rcmb.2013-0179oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027832724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.164.10.2101083", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030324537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01902140701509458", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030373341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0945-053x(99)00031-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030657339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.resp.2012.01.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031513987"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01902140303761", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037311907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/arrd.1976.113.6.787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039380518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/019021490951522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045269978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/019021490951522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045269978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.90924.2008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051011332"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/ajrccm.164.5.2010032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051534279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/09031936.03.00047603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051723270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.277.5334.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062558114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082431325", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082807933", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083175921", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017", 
    "datePublishedReg": "2017-01-01", 
    "description": "Pulmonary emphysema is one of the distinct pathological forms of chronic obstructive pulmonary disease (COPD) that is accompanied by gradual elimination of alveolar tissue, causing reductions in lung recoil and leading to difficulty in breathing. As there is no cure for emphysema, animal models are often used to better understand the pathogenesis and progression of the disease. One widely used animal model of emphysema is the elastase treatment. In this chapter, we describe two methods of elastase-induced emphysema in mice. The first is a single-dose treatment, whereby elastase is introduced oropharengeally into the lung and the structure and/or function of the lungs are studied between 2 days and 4 weeks following the treatment. The second method consists of exposing mice repeatedly (four times) to elastase intratracheally and observing the effects of the treatment 1-4 weeks following the last administration of the enzyme. Both protocols are described in detail, and examples of lung structure and function of the emphysematous mouse lung are provided.", 
    "editor": [
      {
        "familyName": "Borel", 
        "givenName": "Florie", 
        "type": "Person"
      }, 
      {
        "familyName": "Mueller", 
        "givenName": "Christian", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4939-7163-3_7", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2543590", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": {
      "isbn": [
        "978-1-4939-7161-9", 
        "978-1-4939-7163-3"
      ], 
      "name": "Alpha-1 Antitrypsin Deficiency", 
      "type": "Book"
    }, 
    "name": "Elastase-Induced Lung Emphysema Models in Mice", 
    "pagination": "67-75", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4939-7163-3_7"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "24e1b6ff013c1f76cf262af9d44f9fe0c2044ef4c885b18e8960b672fe16fac3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1090910130"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28752447"
        ]
      }
    ], 
    "publisher": {
      "location": "New York, NY", 
      "name": "Springer New York", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4939-7163-3_7", 
      "https://app.dimensions.ai/details/publication/pub.1090910130"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-16T00:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000601.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4939-7163-3_7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-7163-3_7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-7163-3_7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-7163-3_7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4939-7163-3_7'


 

This table displays all metadata directly associated to this object as RDF triples.

198 TRIPLES      23 PREDICATES      61 URIs      29 LITERALS      17 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4939-7163-3_7 schema:about N14ad64ae6e01440b8c2d769163f36693
2 N48be4f6464b64259b67efe7f2a00896c
3 N4a056a51dddf42dfad2b4f17eca28f47
4 N66e37b10140f4ba6b371977432b270ff
5 N731b55e4bdcc43f3aae0e3523716a300
6 N9fcd133e9ce5460e8431fdcccc73b566
7 Nbe6466cfc0d4444dbb43dd26e206d68d
8 Ndc6795dbb3744c8b9fd6df01abb1c2c3
9 anzsrc-for:11
10 anzsrc-for:1102
11 schema:author N4bbe4628c5434fcd91ae0407089e34bb
12 schema:citation sg:pub.10.1186/s12931-014-0118-x
13 https://app.dimensions.ai/details/publication/pub.1082431325
14 https://app.dimensions.ai/details/publication/pub.1082807933
15 https://app.dimensions.ai/details/publication/pub.1083175921
16 https://doi.org/10.1016/0014-4800(92)90033-8
17 https://doi.org/10.1016/j.resp.2012.01.002
18 https://doi.org/10.1016/s0945-053x(99)00031-1
19 https://doi.org/10.1073/pnas.1007625107
20 https://doi.org/10.1080/01902140303761
21 https://doi.org/10.1080/01902140590918669
22 https://doi.org/10.1080/01902140701509458
23 https://doi.org/10.1080/019021490951522
24 https://doi.org/10.1126/science.277.5334.2002
25 https://doi.org/10.1136/thorax.2003.006494
26 https://doi.org/10.1152/japplphysiol.00424.2005
27 https://doi.org/10.1152/japplphysiol.00590.2004
28 https://doi.org/10.1152/japplphysiol.90924.2008
29 https://doi.org/10.1164/ajrccm.164.10.2101083
30 https://doi.org/10.1164/ajrccm.164.5.2010032
31 https://doi.org/10.1164/arrd.1976.113.6.787
32 https://doi.org/10.1165/rcmb.2008-0424oc
33 https://doi.org/10.1165/rcmb.2010-0473oc
34 https://doi.org/10.1165/rcmb.2013-0179oc
35 https://doi.org/10.1183/09031936.03.00047603
36 https://doi.org/10.1371/journal.pmed.0030442
37 schema:datePublished 2017
38 schema:datePublishedReg 2017-01-01
39 schema:description Pulmonary emphysema is one of the distinct pathological forms of chronic obstructive pulmonary disease (COPD) that is accompanied by gradual elimination of alveolar tissue, causing reductions in lung recoil and leading to difficulty in breathing. As there is no cure for emphysema, animal models are often used to better understand the pathogenesis and progression of the disease. One widely used animal model of emphysema is the elastase treatment. In this chapter, we describe two methods of elastase-induced emphysema in mice. The first is a single-dose treatment, whereby elastase is introduced oropharengeally into the lung and the structure and/or function of the lungs are studied between 2 days and 4 weeks following the treatment. The second method consists of exposing mice repeatedly (four times) to elastase intratracheally and observing the effects of the treatment 1-4 weeks following the last administration of the enzyme. Both protocols are described in detail, and examples of lung structure and function of the emphysematous mouse lung are provided.
40 schema:editor N6082de9c681f445c9ecda37eec5bfd2a
41 schema:genre chapter
42 schema:inLanguage en
43 schema:isAccessibleForFree false
44 schema:isPartOf Na3961151411a4335a714785ca7a87a7a
45 schema:name Elastase-Induced Lung Emphysema Models in Mice
46 schema:pagination 67-75
47 schema:productId N0011a0f5bfe84d58b34e393313d2f03d
48 N648d766eab704679a00f97685c0af848
49 Ne94a7c183e70464e9700db4a1c1c5e81
50 Ne9e55e2cc3544044bfdec22630ba95bf
51 schema:publisher N6467c2bb9c2d4d178e6ff0127228b286
52 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090910130
53 https://doi.org/10.1007/978-1-4939-7163-3_7
54 schema:sdDatePublished 2019-04-16T00:31
55 schema:sdLicense https://scigraph.springernature.com/explorer/license/
56 schema:sdPublisher Ne774d027db6e483da8c353799a78e482
57 schema:url http://link.springer.com/10.1007/978-1-4939-7163-3_7
58 sgo:license sg:explorer/license/
59 sgo:sdDataset chapters
60 rdf:type schema:Chapter
61 N0011a0f5bfe84d58b34e393313d2f03d schema:name readcube_id
62 schema:value 24e1b6ff013c1f76cf262af9d44f9fe0c2044ef4c885b18e8960b672fe16fac3
63 rdf:type schema:PropertyValue
64 N13b9976cc26b49bf8c3ebad435924265 schema:familyName Mueller
65 schema:givenName Christian
66 rdf:type schema:Person
67 N14ad64ae6e01440b8c2d769163f36693 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Animals
69 rdf:type schema:DefinedTerm
70 N2112f325f206449bbdcd66f6d5d9b0e2 rdf:first sg:person.012174761157.42
71 rdf:rest rdf:nil
72 N48be4f6464b64259b67efe7f2a00896c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name Pancreatic Elastase
74 rdf:type schema:DefinedTerm
75 N4a056a51dddf42dfad2b4f17eca28f47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Mice, Inbred BALB C
77 rdf:type schema:DefinedTerm
78 N4bbe4628c5434fcd91ae0407089e34bb rdf:first sg:person.0730323706.34
79 rdf:rest Nc20f62735ea14c8c89dfae613998abd8
80 N6082de9c681f445c9ecda37eec5bfd2a rdf:first N65c31edd59794b88a6f4ffc3eca00dca
81 rdf:rest N940579b2ae6746b9b4efb968b87dea7c
82 N6467c2bb9c2d4d178e6ff0127228b286 schema:location New York, NY
83 schema:name Springer New York
84 rdf:type schema:Organisation
85 N648d766eab704679a00f97685c0af848 schema:name pubmed_id
86 schema:value 28752447
87 rdf:type schema:PropertyValue
88 N65c31edd59794b88a6f4ffc3eca00dca schema:familyName Borel
89 schema:givenName Florie
90 rdf:type schema:Person
91 N66e37b10140f4ba6b371977432b270ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Collagen
93 rdf:type schema:DefinedTerm
94 N731b55e4bdcc43f3aae0e3523716a300 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Mice, Inbred C57BL
96 rdf:type schema:DefinedTerm
97 N940579b2ae6746b9b4efb968b87dea7c rdf:first N13b9976cc26b49bf8c3ebad435924265
98 rdf:rest rdf:nil
99 N9fcd133e9ce5460e8431fdcccc73b566 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Disease Models, Animal
101 rdf:type schema:DefinedTerm
102 Na3961151411a4335a714785ca7a87a7a schema:isbn 978-1-4939-7161-9
103 978-1-4939-7163-3
104 schema:name Alpha-1 Antitrypsin Deficiency
105 rdf:type schema:Book
106 Nbe6466cfc0d4444dbb43dd26e206d68d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Pulmonary Emphysema
108 rdf:type schema:DefinedTerm
109 Nc20f62735ea14c8c89dfae613998abd8 rdf:first sg:person.010506062527.53
110 rdf:rest N2112f325f206449bbdcd66f6d5d9b0e2
111 Ndc6795dbb3744c8b9fd6df01abb1c2c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Sus scrofa
113 rdf:type schema:DefinedTerm
114 Ne774d027db6e483da8c353799a78e482 schema:name Springer Nature - SN SciGraph project
115 rdf:type schema:Organization
116 Ne94a7c183e70464e9700db4a1c1c5e81 schema:name dimensions_id
117 schema:value pub.1090910130
118 rdf:type schema:PropertyValue
119 Ne9e55e2cc3544044bfdec22630ba95bf schema:name doi
120 schema:value 10.1007/978-1-4939-7163-3_7
121 rdf:type schema:PropertyValue
122 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
123 schema:name Medical and Health Sciences
124 rdf:type schema:DefinedTerm
125 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
126 schema:name Cardiorespiratory Medicine and Haematology
127 rdf:type schema:DefinedTerm
128 sg:grant.2543590 http://pending.schema.org/fundedItem sg:pub.10.1007/978-1-4939-7163-3_7
129 rdf:type schema:MonetaryGrant
130 sg:person.010506062527.53 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
131 schema:familyName Bartolák-Suki
132 schema:givenName Erzsébet
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010506062527.53
134 rdf:type schema:Person
135 sg:person.012174761157.42 schema:affiliation https://www.grid.ac/institutes/grid.8536.8
136 schema:familyName Rocco
137 schema:givenName Patricia R. M.
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012174761157.42
139 rdf:type schema:Person
140 sg:person.0730323706.34 schema:affiliation https://www.grid.ac/institutes/grid.189504.1
141 schema:familyName Suki
142 schema:givenName Béla
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730323706.34
144 rdf:type schema:Person
145 sg:pub.10.1186/s12931-014-0118-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021154228
146 https://doi.org/10.1186/s12931-014-0118-x
147 rdf:type schema:CreativeWork
148 https://app.dimensions.ai/details/publication/pub.1082431325 schema:CreativeWork
149 https://app.dimensions.ai/details/publication/pub.1082807933 schema:CreativeWork
150 https://app.dimensions.ai/details/publication/pub.1083175921 schema:CreativeWork
151 https://doi.org/10.1016/0014-4800(92)90033-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004367015
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/j.resp.2012.01.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031513987
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/s0945-053x(99)00031-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030657339
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1073/pnas.1007625107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021244161
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1080/01902140303761 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037311907
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1080/01902140590918669 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014743019
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1080/01902140701509458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030373341
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1080/019021490951522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045269978
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1126/science.277.5334.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062558114
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1136/thorax.2003.006494 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018312000
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1152/japplphysiol.00424.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013894166
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1152/japplphysiol.00590.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022223453
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1152/japplphysiol.90924.2008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051011332
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1164/ajrccm.164.10.2101083 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030324537
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1164/ajrccm.164.5.2010032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051534279
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1164/arrd.1976.113.6.787 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039380518
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1165/rcmb.2008-0424oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1021776128
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1165/rcmb.2010-0473oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1000162327
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1165/rcmb.2013-0179oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1027832724
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1183/09031936.03.00047603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051723270
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1371/journal.pmed.0030442 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002063116
192 rdf:type schema:CreativeWork
193 https://www.grid.ac/institutes/grid.189504.1 schema:alternateName Boston University
194 schema:name Boston University
195 rdf:type schema:Organization
196 https://www.grid.ac/institutes/grid.8536.8 schema:alternateName Federal University of Rio de Janeiro
197 schema:name Federal University of Rio de Janeiro
198 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...