Uncovering Metabolic Effects of Anti-angiogenic Therapy in Tumors by Induced Metabolic Bioluminescence Imaging View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Stefano Indraccolo , Stefan Walenta , Wolfgang Mueller-Klieser

ABSTRACT

Induced metabolic bioluminescence imaging (imBI) is an imaging technique which enables detection of various metabolites associated with glycolysis in tumor sections. Signals captured by imBI can be used to chart the topographic distribution of lactate, glucose, pyruvate, and ATP and quantify their absolute amount. ImBi can enable us to perform metabolic classification of tumors as well as to detect metabolic changes in the glycolytic pathway associated with certain therapies, such as anti-angiogenic drugs. More... »

PAGES

175-184

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-3999-2_16

DOI

http://dx.doi.org/10.1007/978-1-4939-3999-2_16

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032836892

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27858366


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