ICOS Expression as Immunologic Marker in Immune Activating Monoclonal Antibodies View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016

AUTHORS

Riccardo Danielli , Ornella Cutaia , Carolina Fazio , Erika Bertocci , Ester Fonsatti , Michele Maio , Luana Calabrò

ABSTRACT

Compelling experimental evidences point to monitoring of the absolute number of circulating ICOS-positive T cells as an early predictive marker of clinical activity of anti-CTLA-4 antibodies in cancer patients. Here, we report available data focusing on this issue and operative procedures to detect ICOS expression on circulating peripheral blood mononuclear cells during CTLA-4 blockade therapy. More... »

PAGES

133-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-3338-9_13

DOI

http://dx.doi.org/10.1007/978-1-4939-3338-9_13

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023428877

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27033223


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