Chemotherapy View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2015

AUTHORS

Arjun Vasant Balar , Matthew D. Galsky , Arlene O. Siefker-Radtke , Scott T. Tagawa , Matthew I. Milowsky

ABSTRACT

Urothelial cancer is a chemotherapy-sensitive pan-urothelial disease that arises from both the upper and lower urinary tract. Due to its rarity, the principles for management of upper tract urothelial cancer are derived from evidence gathered in bladder cancer trials. To date, no definitive evidence has differentiated upper tract from lower tract cancer and both are managed similarly. Epidemiologic observations, tissue-based genetic studies, and recent subset analyses from randomized trials suggest potential differences between upper tract and bladder cancers which will need to be validated in prospective trials. This chapter will review the current role for perioperative chemotherapy in high-grade upper tract urothelial cancer as well as the use of chemotherapy in advanced disease. More... »

PAGES

179-189

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-1501-9_8

DOI

http://dx.doi.org/10.1007/978-1-4939-1501-9_8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004497650


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