Sleep and the Esophagus View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

John P. Lazenby , Susan M. Harding

ABSTRACT

The functional anatomy of the esophagus is complex, and both esophageal function and esophageal acid clearance are altered during sleep. Gastroesophageal reflux disease (GER), a chronic disorder, is the most common disease affecting the esophagus, and GER symptoms may occur throughout the 24-h period or may be limited to sleep time. Sleep-related GER can have significant effects on daytime functioning and quality of life. In addition, prolonged esophageal acid contact times associated with reflux during sleep increase the risk of erosive esophagitis, Barrett’s esophagus, and extra-esophageal manifestations of GER such as nocturnal asthma and sleep-related laryngospasm. Treatment of sleep-related GER includes conservative measures, acid-reducing medications such as proton pump inhibitors, and surgical fundoplication. Other therapies are under investigation. Sleep-related GER shares a complex and poorly understood relationship with obstructive sleep apnea (OSA), and continuous positive airway pressure (CPAP) has been shown to improve symptoms associated with sleep-related GER. More... »

PAGES

283-295

References to SciGraph publications

Book

TITLE

Primary Care Sleep Medicine

ISBN

978-1-4939-1184-4
978-1-4939-1185-1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-1185-1_26

DOI

http://dx.doi.org/10.1007/978-1-4939-1185-1_26

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018447800


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