Target Selection for Structural Genomics of Infectious Diseases View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

Corin Yeats , Benoit H. Dessailly , Elizabeth M. Glass , Daved H. Fremont , Christine A. Orengo

ABSTRACT

This chapter describes the protocols used to identify, filter, and annotate potential protein targets from an organism associated with infectious diseases. Protocols often combine computational approaches for mining information in public databases or for checking whether the protein has already been targeted for structure determination, with manual strategies that examine the literature for information on the biological role of the protein or the experimental strategies that explore the effects of knocking out the protein. Publicly available computational tools have been cited as much as possible. Where these do not exist, the concepts underlying in-house tools developed for the Center for Structural Genomics of Infectious Diseases have been described. More... »

PAGES

35-51

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4939-0354-2_3

DOI

http://dx.doi.org/10.1007/978-1-4939-0354-2_3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036719247

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24590707


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