Fetal Lower Urinary Tract Physiology: In Vivo Studies View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1995

AUTHORS

Robert A. Mevorach , Barry A. Kogan

ABSTRACT

Fetal urine is an important contributor to amniotic fluid, and hence there is no question that the fetus voids in utero. However, the maturation of the fetal lower urinary tract function has not been studied extensively. Nonetheless, defining the developmental changes is critical to understanding the pathophysiology of abnormal voiding, both pre- and post-natally. For example, the long-term bladder problems in patients with posterior urethral valves, which can cause renal insufficiency, are directly related to developmental changes owing to the obstruction. Furthermore, abnormalities of lower urinary tract function are seen prenatally and result in problems with urine storage and elimination even before birth. As a consequence, some instances of prenatal hydronephrosis may be caused by in utero vesico-sphincteric dysfunction (Kopp and Greenfield 1993). Furthermore, the advent of many new technologies in the evaluation and treatment of fetal abnormalities now allows for intervention, in the form of decompression of the urinary tract, in cases of in utero hydronephrosis. Because these interventions are technically feasible, it behooves us to understand better the physiology of fetal lower urinary tract function in to direct treatment more effectively. As we improve our understanding of normal bladder and sphincteric function in the fetus, we will be able to distinguish better between innocent urinary tract changes worthy of observation and significant lower urinary tract disorders for which therapeutic intervention would be advantageous. More... »

PAGES

85-91

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4899-1585-6_11

DOI

http://dx.doi.org/10.1007/978-1-4899-1585-6_11

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052541914

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8571849


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Paediatrics and Reproductive Medicine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pregnancy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ultrasonography, Prenatal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urinary Bladder", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urinary Tract", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Urinary Tract Physiological Phenomena", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Urology, University of California School of Medicine, 94143-0738, San Francisco, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.30389.31", 
          "name": [
            "Department of Urology, University of California School of Medicine, 94143-0738, San Francisco, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mevorach", 
        "givenName": "Robert A.", 
        "id": "sg:person.010271237167.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010271237167.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Urology, University of California School of Medicine, 94143-0738, San Francisco, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.30389.31", 
          "name": [
            "Department of Urology, University of California School of Medicine, 94143-0738, San Francisco, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kogan", 
        "givenName": "Barry A.", 
        "id": "sg:person.01257435113.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257435113.04"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1995", 
    "datePublishedReg": "1995-01-01", 
    "description": "Fetal urine is an important contributor to amniotic fluid, and hence there is no question that the fetus voids in utero. However, the maturation of the fetal lower urinary tract function has not been studied extensively. Nonetheless, defining the developmental changes is critical to understanding the pathophysiology of abnormal voiding, both pre- and post-natally. For example, the long-term bladder problems in patients with posterior urethral valves, which can cause renal insufficiency, are directly related to developmental changes owing to the obstruction. Furthermore, abnormalities of lower urinary tract function are seen prenatally and result in problems with urine storage and elimination even before birth. As a consequence, some instances of prenatal hydronephrosis may be caused by in utero vesico-sphincteric dysfunction (Kopp and Greenfield 1993). Furthermore, the advent of many new technologies in the evaluation and treatment of fetal abnormalities now allows for intervention, in the form of decompression of the urinary tract, in cases of in utero hydronephrosis. Because these interventions are technically feasible, it behooves us to understand better the physiology of fetal lower urinary tract function in to direct treatment more effectively. As we improve our understanding of normal bladder and sphincteric function in the fetus, we will be able to distinguish better between innocent urinary tract changes worthy of observation and significant lower urinary tract disorders for which therapeutic intervention would be advantageous.", 
    "editor": [
      {
        "familyName": "Zderic", 
        "givenName": "Stephen A.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4899-1585-6_11", 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4899-1587-0", 
        "978-1-4899-1585-6"
      ], 
      "name": "Muscle, Matrix, and Bladder Function", 
      "type": "Book"
    }, 
    "keywords": [
      "lower urinary tract function", 
      "urinary tract function", 
      "tract function", 
      "lower urinary tract disorders", 
      "form of decompression", 
      "urinary tract changes", 
      "posterior urethral valves", 
      "urinary tract disorders", 
      "renal insufficiency", 
      "urethral valves", 
      "abnormal voiding", 
      "prenatal hydronephrosis", 
      "bladder problems", 
      "sphincteric function", 
      "urinary tract", 
      "tract disorders", 
      "fetal urine", 
      "normal bladder", 
      "tract changes", 
      "developmental changes", 
      "amniotic fluid", 
      "urine storage", 
      "therapeutic interventions", 
      "fetal abnormalities", 
      "vivo studies", 
      "hydronephrosis", 
      "intervention", 
      "abnormalities", 
      "direct treatment", 
      "treatment", 
      "important contributor", 
      "patients", 
      "pathophysiology", 
      "dysfunction", 
      "bladder", 
      "obstruction", 
      "utero", 
      "insufficiency", 
      "fetuses", 
      "voiding", 
      "tract", 
      "decompression", 
      "urine", 
      "disorders", 
      "birth", 
      "changes", 
      "maturation", 
      "function", 
      "physiology", 
      "valve", 
      "evaluation", 
      "cases", 
      "elimination", 
      "study", 
      "contributor", 
      "fluid", 
      "advent", 
      "consequences", 
      "understanding", 
      "questions", 
      "observations", 
      "new technologies", 
      "form", 
      "instances", 
      "problem", 
      "storage", 
      "technology", 
      "example", 
      "voids"
    ], 
    "name": "Fetal Lower Urinary Tract Physiology: In Vivo Studies", 
    "pagination": "85-91", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1052541914"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4899-1585-6_11"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8571849"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4899-1585-6_11", 
      "https://app.dimensions.ai/details/publication/pub.1052541914"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-12-01T06:51", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/chapter/chapter_332.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-1-4899-1585-6_11"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4899-1585-6_11'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4899-1585-6_11'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4899-1585-6_11'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4899-1585-6_11'


 

This table displays all metadata directly associated to this object as RDF triples.

171 TRIPLES      22 PREDICATES      103 URIs      96 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4899-1585-6_11 schema:about N090c4f69ef654dc18f6b6a77167c9184
2 N8218254bae56418289f2839069087ac4
3 N893a1835b5aa41c6a4188974050f1ba6
4 Nb62786e9cb234b3989bc6ae8259fc172
5 Nde1818fe0c354185ba731493a4a645c8
6 Ndfd08d5ec29c41f18532c6ebb2d4f4d6
7 Nec1e6a76ca9f48ba86574aea7d4696c6
8 Nf930db135f494c0aa750aa4b3615e3c7
9 anzsrc-for:11
10 anzsrc-for:1114
11 schema:author Nb5f27df27e9145f9ad5a2f98bd368d83
12 schema:datePublished 1995
13 schema:datePublishedReg 1995-01-01
14 schema:description Fetal urine is an important contributor to amniotic fluid, and hence there is no question that the fetus voids in utero. However, the maturation of the fetal lower urinary tract function has not been studied extensively. Nonetheless, defining the developmental changes is critical to understanding the pathophysiology of abnormal voiding, both pre- and post-natally. For example, the long-term bladder problems in patients with posterior urethral valves, which can cause renal insufficiency, are directly related to developmental changes owing to the obstruction. Furthermore, abnormalities of lower urinary tract function are seen prenatally and result in problems with urine storage and elimination even before birth. As a consequence, some instances of prenatal hydronephrosis may be caused by in utero vesico-sphincteric dysfunction (Kopp and Greenfield 1993). Furthermore, the advent of many new technologies in the evaluation and treatment of fetal abnormalities now allows for intervention, in the form of decompression of the urinary tract, in cases of in utero hydronephrosis. Because these interventions are technically feasible, it behooves us to understand better the physiology of fetal lower urinary tract function in to direct treatment more effectively. As we improve our understanding of normal bladder and sphincteric function in the fetus, we will be able to distinguish better between innocent urinary tract changes worthy of observation and significant lower urinary tract disorders for which therapeutic intervention would be advantageous.
15 schema:editor N4c7cd79dd9d342bd957bda3ad6c672dd
16 schema:genre chapter
17 schema:isAccessibleForFree false
18 schema:isPartOf N1d56a72daa084d93b3df3b34c1e4323c
19 schema:keywords abnormal voiding
20 abnormalities
21 advent
22 amniotic fluid
23 birth
24 bladder
25 bladder problems
26 cases
27 changes
28 consequences
29 contributor
30 decompression
31 developmental changes
32 direct treatment
33 disorders
34 dysfunction
35 elimination
36 evaluation
37 example
38 fetal abnormalities
39 fetal urine
40 fetuses
41 fluid
42 form
43 form of decompression
44 function
45 hydronephrosis
46 important contributor
47 instances
48 insufficiency
49 intervention
50 lower urinary tract disorders
51 lower urinary tract function
52 maturation
53 new technologies
54 normal bladder
55 observations
56 obstruction
57 pathophysiology
58 patients
59 physiology
60 posterior urethral valves
61 prenatal hydronephrosis
62 problem
63 questions
64 renal insufficiency
65 sphincteric function
66 storage
67 study
68 technology
69 therapeutic interventions
70 tract
71 tract changes
72 tract disorders
73 tract function
74 treatment
75 understanding
76 urethral valves
77 urinary tract
78 urinary tract changes
79 urinary tract disorders
80 urinary tract function
81 urine
82 urine storage
83 utero
84 valve
85 vivo studies
86 voiding
87 voids
88 schema:name Fetal Lower Urinary Tract Physiology: In Vivo Studies
89 schema:pagination 85-91
90 schema:productId N1e017ec6fd2c42eda4bd95e7859bb1ef
91 N99a29d73a81844ab9a548e6754793fdf
92 Nde814149f0a54d4f8fb5af1bd3e127f0
93 schema:publisher N5b2aab6b879240809f388642bdfa9f97
94 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052541914
95 https://doi.org/10.1007/978-1-4899-1585-6_11
96 schema:sdDatePublished 2022-12-01T06:51
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher N33efdd96cd2c43f783c2cdc7c63dd04c
99 schema:url https://doi.org/10.1007/978-1-4899-1585-6_11
100 sgo:license sg:explorer/license/
101 sgo:sdDataset chapters
102 rdf:type schema:Chapter
103 N090c4f69ef654dc18f6b6a77167c9184 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Humans
105 rdf:type schema:DefinedTerm
106 N1d56a72daa084d93b3df3b34c1e4323c schema:isbn 978-1-4899-1585-6
107 978-1-4899-1587-0
108 schema:name Muscle, Matrix, and Bladder Function
109 rdf:type schema:Book
110 N1e017ec6fd2c42eda4bd95e7859bb1ef schema:name doi
111 schema:value 10.1007/978-1-4899-1585-6_11
112 rdf:type schema:PropertyValue
113 N33efdd96cd2c43f783c2cdc7c63dd04c schema:name Springer Nature - SN SciGraph project
114 rdf:type schema:Organization
115 N4c7cd79dd9d342bd957bda3ad6c672dd rdf:first N7aaa001682f84481bdbbf2e0a9a60a9c
116 rdf:rest rdf:nil
117 N5b2aab6b879240809f388642bdfa9f97 schema:name Springer Nature
118 rdf:type schema:Organisation
119 N7aaa001682f84481bdbbf2e0a9a60a9c schema:familyName Zderic
120 schema:givenName Stephen A.
121 rdf:type schema:Person
122 N8218254bae56418289f2839069087ac4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Animals
124 rdf:type schema:DefinedTerm
125 N85dc346e602b4c6e909b9ba396e5e767 rdf:first sg:person.01257435113.04
126 rdf:rest rdf:nil
127 N893a1835b5aa41c6a4188974050f1ba6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Urinary Tract Physiological Phenomena
129 rdf:type schema:DefinedTerm
130 N99a29d73a81844ab9a548e6754793fdf schema:name dimensions_id
131 schema:value pub.1052541914
132 rdf:type schema:PropertyValue
133 Nb5f27df27e9145f9ad5a2f98bd368d83 rdf:first sg:person.010271237167.18
134 rdf:rest N85dc346e602b4c6e909b9ba396e5e767
135 Nb62786e9cb234b3989bc6ae8259fc172 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Urinary Bladder
137 rdf:type schema:DefinedTerm
138 Nde1818fe0c354185ba731493a4a645c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Urinary Tract
140 rdf:type schema:DefinedTerm
141 Nde814149f0a54d4f8fb5af1bd3e127f0 schema:name pubmed_id
142 schema:value 8571849
143 rdf:type schema:PropertyValue
144 Ndfd08d5ec29c41f18532c6ebb2d4f4d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Ultrasonography, Prenatal
146 rdf:type schema:DefinedTerm
147 Nec1e6a76ca9f48ba86574aea7d4696c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Pregnancy
149 rdf:type schema:DefinedTerm
150 Nf930db135f494c0aa750aa4b3615e3c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Female
152 rdf:type schema:DefinedTerm
153 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
154 schema:name Medical and Health Sciences
155 rdf:type schema:DefinedTerm
156 anzsrc-for:1114 schema:inDefinedTermSet anzsrc-for:
157 schema:name Paediatrics and Reproductive Medicine
158 rdf:type schema:DefinedTerm
159 sg:person.010271237167.18 schema:affiliation grid-institutes:grid.30389.31
160 schema:familyName Mevorach
161 schema:givenName Robert A.
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010271237167.18
163 rdf:type schema:Person
164 sg:person.01257435113.04 schema:affiliation grid-institutes:grid.30389.31
165 schema:familyName Kogan
166 schema:givenName Barry A.
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257435113.04
168 rdf:type schema:Person
169 grid-institutes:grid.30389.31 schema:alternateName Department of Urology, University of California School of Medicine, 94143-0738, San Francisco, CA, USA
170 schema:name Department of Urology, University of California School of Medicine, 94143-0738, San Francisco, CA, USA
171 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...