The Risk of Insulin-Dependent Diabetes in Offspring of Parents with Insulin-Dependent Diabetes View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1994

AUTHORS

Toomas Podar , Jaakko Tuomilehto , Eva Tuomilehto-Wolf , Ronald E. LaPorte , Janice S. Dorman

ABSTRACT

Some diseases occur more frequently in relatives of affected individuals than in the general population. They do not always follow a pattern within family pedigrees which would fit adequately any known genetic model.1 Insulin-dependent diabetes mellitus (IDDM) is one such disorder. In the pathogenesis of IDDM, specific environmental factors appear to operate on a susceptible genetic background which leads to the occurrence of disease. Although the mode of inheritance of IDDM remains unclear, there is no doubt that the genetic factors are major determinants of the risk of IDDM. The environmental factors responsible for the occurrence of IDDM are less well characterized than the genetic determinants of the disease. More... »

PAGES

57-67

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4899-1213-8_10

DOI

http://dx.doi.org/10.1007/978-1-4899-1213-8_10

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017721628


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