Ether Lipid Metabolism, GPI Anchor Biosynthesis, and Signal Transduction are Putative Targets for Anti-Leishmanial Alkyl Phospholipid Analogues View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1996

AUTHORS

H. Lux , D. T. Hart , P. J. Parker , T. Klenner

ABSTRACT

Leishmaniasis is a tropical and subtropical disease with up to 12 million sufferers and is the cause of considerable morbidity and mortality (WHO-TDR 1990). The causative agent is Leishmania a genus of parasitic protozoa and member of the Trypanosomatidae. Leishmania has a digenic life cycle and exists as a flagellated and motile promastigote stage in the digestive tract of the sandfly vector and as an aflagellated and non-motile intracellular amastigote stage, which survive and multiply in macrophages of the vertebrate host. More... »

PAGES

201-11

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4899-0179-8_33

DOI

http://dx.doi.org/10.1007/978-1-4899-0179-8_33

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002936283

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9131149


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